 | Beau Ances MD, PhD Assistant Professor of Neurology
Theraputic Strategies for HIV Associated Neurocognitive Impairment |
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 | Randall Bateman M.D. Assistant Professor of Neurology
Alzheimer's disease: Pathophysiology, biomarkers, predictive diagnostics and treatments |
|  | Philip V. Bayly Ph.D. Hughes Professor of Mechanical Engineering; Professor of Biomedical Engineering
Biomechanical factors in traumatic injury to the brain and spinal cord |
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 | Janice E. Brunstrom M.D. Associate Professor of Neurology and Pediatrics; Director of the Pediatric Neurology Cerebral Palsy Center at St. Louis Children's Hospital
Motor disorders arising from injury to the developing brain |
|  | Guojun Bu Ph.D. Professor of Pediatrics and Cell Biology & Physiology
LDL receptor family members in human disease |
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 | Nigel Cairns Ph.D., MRCPath Research Associate Professor of Neurology and Pathology & Immunology; Director, Betty Martz Laboratory for Neurodegenerative Research
Protein misfolding, inclusion formation and neurodegeneration in Frontotemporal Dementias |
|  | Valeria Cavalli Ph.D. Assistant Professor of Anatomy and Neurobiology
Axonal Transport, Injury Signaling and Nerve Regeneration |
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 | Anne H. Cross M.D. Professor of Neurology; Manny and Rosalyn Rosenthal and Dr. John Trotter MS Center Chair in Neuroimmunology; Director, Multiple Sclerosis Center
Neuroimmunology related to multiple sclerosis |
|  | C. Michael Crowder M.D., Ph.D. Associate Professor of Anesthesiology and Developmental Biology
Fundamental mechanisms of neuronal cell death following hypoxic injury |
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|  | Marc I. Diamond MD Associate Professor of Neurology
Therapeutic Mechanisms in Human Disease: Polyglutamine Disease Pathogenesis and Protein Misfolding in Tauopathy |
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 | Aaron DiAntonio M.D., Ph.D. Associate Professor of Developmental Biology
Mechanisms of synaptic structure and function during development |
|  | Hans H. Dietrich Ph.D. Research Assistant Professor of Neurological Surgery
Regulatory mechanisms of cerebrovascular microcirculation |
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 | Gerald W. Dorn II MD Philip and Sima K. Needleman Professor of Medicine
Caridiac Disease and Signaling Pathways for Heart Cell Growth and Death |
|  | Alex S. Evers M.D. Henry E. Mallinckrodt Professor and Head of Anesthesiology; Professor of Internal Medicine and Developmental Biology
Molecular mechanisms of anesthetics in the nervous system |
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 | Anne M. Fagan Niven Ph.D. Research Associate Professor of Neurology
Biomarkers, and mechanisms of apoE4 action in Alzheimer's Disease |
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 | Carl Frieden Ph.D. Professor of Biochemistry & Molecular Biophysics
Protein folding, structure |
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|  | Jeffrey M. Gidday Ph.D. Associate Professor of Neurological Surgery
Endogenous mechanisms of vascular and parenchymal protection in CNS ischemia. |
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 | Alison M. Goate D.Phil. Samuel and Mae S. Ludwig Chair in Psychiatry; Professor of Neurology and Genetics; Hope Center Steering Committee
Linkage and association studies to uncover genetic susceptibility to neuropsychiatric disease. |
|  | Mark P. Goldberg M.D. Professor of Neurology, Neurobiology, and Biomedical Engineering; Director of the Hope Center for Neurological Disorders
Mechanisms of ischemic injury and recovery in white matter axons and glia. |
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|  | Phyllis I. Hanson M.D., Ph.D. Associate Professor of Cell Biology and Physiology
Protein-protein and protein-membrane interactions in neuronal membrane trafficking. |
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 | David M. Holtzman M.D. Andrew B. and Gretchen P. Jones Professor and Chairman of Neurology; Professor of Molecular Biology; Hope Center Steering Committee
Cellular/Molecular/Biomarkers studies of Alzheimer's disease and neonatal brain injury. |
|  | Mark Jacquin Ph.D. Professor of Neurology
Molecular mechanisms of mammalian sensory system development, plasticity and repair. |
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 | Sanjay Jain M.D., Ph.D. Assistant Professor of Internal Medicine (Renal) and Pathology & Immunology
GFL-Ret mediated mechanisms in the development, repair and regeneration of the nervous and urogenital systems |
|  | Eugene M. Johnson Ph.D. Professor of Neurology and Developmental Biology; Hope Center Steering Committee
Biological function and pharmacological potential of GFL neurotrophic factors |
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 | Robyn S. Klein M.D., Ph.D. Assistant Professor of Internal Medicine
Molecular basis of inflammation-associated dysfunction in viral and autoimmune encephalitides |
|  | Vitaly Klyachko PhD Assistant Professor of Biomedical Engineering and Cell Biology and Physiology
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 | Raphael Kopan Ph.D. Professor of Internal Medicine and Developmental Biology
Studies of cell fate determination in mammalian system with focus on Notch mediated signal transduction. |
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 | Jin-Moo Lee M.D., Ph.D. Associate Professor of Neurology
Understanding the molecular pathogenesis of spontaneous intracerebral hemorrhage |
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 | Susan Mackinnon M.D. Shoenberg Professor, Chief, Division of Plastic and Reconstructive Surgery
Allograft and the Effects of GDNF on Peripheral Nerve Regeneration |
|  | Steven J. Mennerick Ph.D. Associate Professor of Psychiatry and Anatomy & Neurobiology
Physiology of glutamate and GABA neurotransmission in the CNS. |
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 | Jeffrey D. Milbrandt M.D., Ph.D. James S. McDonnell Professor and Head of the Department of Genetics, Professor of Neurology; Professor of Pathology & Immunology and Internal Medicine; Hope Center Steering Committee
Axonal degeneration, regulation of myelination, neuronal energetics and mitochondrial function in neuropathy and neurodegenerative disease |
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 | Jeanne M. Nerbonne Ph.D. Alumni Endowed Professor of Developmental Biology
Molecular mechanisms controlling the function, expression and properties of voltage-gated K channels in cardiac and neuronal cells |
|  | Karen L. O'Malley Ph.D. Professor of Anatomy and Neurobiology
Mechanisms underlying the specification, regulation, and neurodegeneration of dopaminergic and glutamatergic systems. |
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 | David M. Ornitz M.D., Ph.D. Alumni Endowed Professor and Interim Chair of Developmental Biology
FGFs in lung, skeletal, cardiovascular and CNS development and function |
|  | Rohit V. Pappu Ph.D. Associate Professor of Biomedical Engineering
Alzheimer's disease; biophysics; mathematical modeling; thermodynamics |
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 | Joel S. Perlmutter M.D. Elliot H. Stein Professor of Neurology; Professor of Radiology and Anatomy & Neurobiology; Head of the Movement Disorders Section
Pharmacology, physiology and pathophysiology of basal ganglia and movement disorders. |
|  | Alan Pestronk M.D. Professor of Neurology and Pathology; Director of the Neuromuscular Division
Diagnosis, pathogenesis and treatment of immune, hereditary and degenerative neuromuscular disorders |
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 | David R. Piwnica-Worms M.D., Ph.D. Professor of Radiology and Developmental Biology
Molecular imaging of gene expression and protein function in vivo; multidrug resistance transporters; metallopharmaceuticals |
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|  | Shelly E. Sakiyama-Elbert Ph.D. Joseph and Florence Farrow Associate Professor of Biomedical Engineering
Tissue and cellular engineering approaches to neurological diseases |
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 | Mark S. Sands Ph.D. Associate Professor of Internal Medicine and Genetics
Pathophysiology and novel therapies for lysosomal storage diseases |
|  | Anneliese M. Schaefer J.D., Ph.D. Director, Office of Neuroscience Research; Research Assistant Professor of Neurology
Pathological changes of axons, motor units, and neuromuscular junctions in motor neuron disease |
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 | Bradley L. Schlaggar M.D., Ph.D. A. Ernest and Jane G. Stein Associate Professor of Developmental Neurology
The development and plasticity of human cognition and language |
|  | Robert E. Schmidt M.D., Ph.D. Professor of Pathology & Immunology; Director, Neuropathology Division
Pathogenetic mechanisms of diabetic and age-related autonomic neuropathy |
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 | B. Joy Snider M.D., Ph.D. Assistant Professor of Neurology
Mechanisms of protein degradation and intracellular calcium homeostasis in neurodegenerative disorders |
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 | Paul H. Taghert Ph.D Professor of Anatomy & Neurobiology
Circadian neurobiology and developmental neurobiology |
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|  | Conrad Chris Weihl M.D., Ph.D. Assistant Professor of Neurology
Protein degradation pathways and their relation to aging, muscle weakness, and neurodegeneration |
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 | Michael Wong M.D., Ph.D. Assistant Professor of Neurology and Pediatrics
Cellular mechanisms of epileptogenesis and seizure-induced brain injury |
|  | David F. Wozniak Ph.D. Research Professor of Psychiatry
Role of NMDA receptors in neuropathologic changes and cognitive decline |
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|  | Kelvin A. Yamada M.D. Associate Professor of Neurology and Pediatrics
Modulation and derangements of synaptic transmission at central nervous system synapses |
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 | Gregory J. Zipfel M.D. Assistant Professor of Neurological Surgery and Neurology
Role of amyloid-B peptide and cerebral amyloid angiopathy in neurovascular dysfunction, ischemic brain injury and subarachnoid hemorrhage |
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