The Hope Center provides resources and facilities to encourage translation of basic science discoveries into therapies for brain diseases. These core facilities are used by Center investigators, and are available to other Washington University investigators. Additional core resources will be developed according to investigator needs and funding.

Hope Center administrative offices and most cores are located in the Biotechnology Center building (old Dental School), 4559 Scott Avenue.

If you have questions or wish to add resources to this list, please send e-mail: HopeCenter@neuro.wustl.edu This email address is being protected from spam bots, you need Javascript enabled to view it .

Hope Center Core resources:

• Alafi Neuroimaging Laboratory - advanced microscopy resources including multiphoton and confocal microscopy, high-throughput slide scanning, and atomic force microscopy
• Amyloid-Beta Microdialysis - continuous measurement of Aβ levels from brain interstitial fluid (ISF) in living mice
• Animal Models Core - rodent models of neurological diseases, including experimental stroke and trauma, stereotaxic microinjection; assistance with mouse and rat animal protocols and model development
• Transgenic Vectors Core - design and construction of mouse transgenes and gene targeting vectors for creation of transgenic mice
• Viral Vectors Core - attenuated viruses for experimental gene delivery, including lentivirus and adeno-associated virus (AAV); assistance with other molecular neuroscience techniques