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Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer’s disease

Posted on January 24, 2020

Yingyue Zhou, Wilbur M. Song, Prabhakar S. Andhey, Amanda Swain, Tyler Levy, Kelly R. Miller, Pietro L. Poliani, Manuela Cominelli, Shikha Grover, Susan Gilfillan, Marina Cella, Tyler K. Ulland, Konstantin Zaitsev, Akinori Miyashita, Takeshi Ikeuchi, Makoto Sainouchi, Akiyoshi Kakita, David A. Bennett, Julie A. Schneider, Michael R. Nichols, Sean A. Beausoleil, Jason D. Ulrich, David M. Holtzman, Maxim N. Artyomov & Marco Colonna . Nature Medicine, Volume 26, Issue 1, 1 January 2020, Pages 131-142 Read More

Posted in: Axon Injury & Repair, Clocks & Sleep, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , ,

Publisher Correction: Dietary salt promotes cognitive impairment through tau phosphorylation (Nature, (2019), 574, 7780, (686-690), 10.1038/s41586-019-1688-z)

Posted on January 23, 2020

Giuseppe Faraco, Karin Hochrainer, Steven G. Segarra, Samantha Schaeffer, Monica M. Santisteban, Ajay Menon, Hong Jiang, David M. Holtzman, Josef Anrather & Costantino Iadecola. Nature 2020 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty:

MeCP2 Represses Enhancers through Chromosome Topology-Associated DNA Methylation

Posted on January 22, 2020

Adam W. Clemens, Dennis Y. Wu, Russell Moore, Diana L. Christian, Guoyan Zhao, Harrison W. Gabel. Molecular Cell, Volume 77, Issue 2, 16 January 2020, Pages 279-293.e8 Read More

Posted in: Neurogenetics & Transcriptomics, Publications Faculty:

TFEB activation in macrophages attenuates postmyocardial infarction ventricular dysfunction independently of ATG5-mediated autophagy

Posted on January 21, 2020

Ali Javaheri, Geetika Bajpai, Antonino Picataggi, Smrithi Mani, Layla Foroughi, Hosannah Evie, Attila Kovacs, Carla J. Weinheimer, Krzystztof Hyrc, Qingli Xiao, Andrea Ballabio, Jin-Moo Lee, Scot J. Matkovich, Babak Razani, Joel D. Schilling, Kory J. Lavine, and Abhinav Diwan. JCI Insight, Volume 4, Issue 21, 1 November 2019, Article number e127312 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: ,

Defining Individual-Specific Functional Neuroanatomy for Precision Psychiatry

Posted on January 21, 2020

Caterina Gratton, Brian T. Kraus, Deanna J. Greene, Evan M. Gordon, Timothy O. Laumann, Steven M. Nelson, Nico U.F. Dosenbach, Steven E. Petersen. Biological Psychiatry 2020 Read More

Posted in: HPAN, Neurodegeneration, Neurovascular Injury & Repair, Publications Faculty: ,