Posted in the category:

Lysosome

Drug trial shows promise for deadly neurological disorder

Posted on August 17, 2017

Cyclodextrin slows progression of Niemann-Pick type C Read More

Posted in: HPAN, Lysosome, Neurodegeneration, News Faculty:

Primary fibroblasts from CSPα mutation carriers recapitulate hallmarks of the adult-onset neuronal ceroid lipofuscinosis

Posted on July 24, 2017

Bruno A. Benitez & Mark S. Sands. 2017 Sci Rep (7) Article Number: 6332 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Pilot Projects, Publications Faculty:

Enhanced Detection of Edema in Malignant Anterior Circulation Stroke (EDEMA) Score

Posted on July 17, 2017

Charlene Jennifer Ong, Jeffrey Gluckstein, Osvaldo Laurido-Soto, Yan Yan, Rajat Dhar, Jin-Moo Lee: 2017 Stroke Volume 48, Issue 7, Pages 1969-1972 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty:

Exploiting macrophage autophagy-lysosomal biogenesis as a therapy for atherosclerosis

Posted on July 10, 2017

Ismail Sergin, Trent D. Evans, Xiangyu Zhang, Somashubhra Bhattacharya, Carl J. Stokes, Eric Song, Sahl Ali, Babak Dehestani, Karyn B. Holloway, Paul S. Micevych, Ali Javaheri, Jan R. Crowley, Andrea Ballabio, Joel D. Schilling, Slava Epelman, Conrad C. Weihl, Abhinav Diwan, Daping Fan, Mohamed A. Zayed & Babak Razani: 2017 Nature Communications Volume 8, 7, Article number 15750 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Publications Faculty: ,

An antidepressant decreases CSF Aβ production in healthy individuals and in transgenic AD mice

Posted on June 28, 2017

Yvette I. Sheline, Tim West, Kevin Yarasheski, Robert Swarm, Mateusz S. Jasielec, Jonathan R. Fisher, Whitney D. Ficker, Ping Yan, Chengjie Xiong, Christine Frederiksen, Monica V. Grzelak, Robert Chott, Randall J. Bateman, John C. Morris, Mark A. Mintun, Jin-Moo Lee and John R. Cirrito: 2014 Sci Transl Med, 10.1126/scitranslmed.3008169 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Neurovascular Injury & Repair, Pilot Projects, Publications Faculty: , , ,