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Clocks & Sleep

TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy

Posted on November 11, 2017

Cheryl E. G. Leyns, Jason D. Ulrich, Mary B. Finn, Floy R. Stewart, Lauren J. Koscal, Javier Remolina Serrano, Grace O. Robinson, Elise Anderson, Marco Colonna, and David M. Holtzman,: Proceedings of the National Academy of Sciences of the United States of America, Volume 114, Issue 43, 24 October 2017, Pages 11524-11529 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: ,

Acute knockdown of Kv4.1 regulates repetitive firing rates and clock gene expression in the suprachiasmatic nucleus and daily rhythms in locomotor behavior

Posted on November 7, 2017

Tracey O. Hermanstyne, Daniel Granados-Fuentes, Rebecca L. Mellor, Erik D. Herzog and Jeanne M. Nerbonne: eNeuro, Volume 4, Issue 3, 2017, Article number e0377-16.2017 Read More

Posted in: Clocks & Sleep, Neurogenetics & Transcriptomics, Publications Faculty: ,

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Posted on November 7, 2017

Lei Du, Kefei Liu, Xiaohui Yao, Jingwen Yan, Shannon L. Risacher, Junwei Han, Lei Guo, Andrew J. Saykin, Li Shen & Alzheimer’s Disease Neuroimaging Initiative: Scientific Reports, Volume 7, Issue 1, 1 December 2017, Article number 14052 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration Faculty: , , , , ,

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

Posted on November 2, 2017

Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno,…et al.: Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty:

C-terminal phosphorylation of NaV1.5 impairs FGF13-dependent regulation of channel inactivation

Posted on November 1, 2017

Sophie Burel, Fabien C. Coyan, Maxime Lorenzini, Matthew R. Meyer, Cheryl F. Lichti, Joan H. Brown, Gildas Loussouarn, Flavien Charpentier, Jeanne M. Nerbonne, R. Reid Townsend, Lars S. Maier and Céline Marionneau: Journal of Biological Chemistry, Volume 292, Issue 42, 2017, Pages 17431-17448 Read More

Posted in: Clocks & Sleep, Neurogenetics & Transcriptomics, Publications Faculty: