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Clocks & Sleep

Mutant huntingtin enhances activation of dendritic Kv4 K + channels in striatal spiny projection neurons

Posted on May 22, 2019

Luis Carrillo-Reid, Michelle Day, Zhong Xie, Alexandria E Melendez, Jyothisri Kondapalli, Joshua L Plotkin, David L Wokosin, Yu Chen, Geraldine J Kress, Michael Kaplitt, Ema Ilijic, Jaime N Guzman, C Savio Chan, D James Surmeier. eLife, Volume 8, 24 April 2019 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty:

Senescent glia spell trouble in Alzheimer’s disease

Posted on May 16, 2019

David Holtzman & Jason Ulrich. Nature Neuroscience, Volume 22, Issue 5, 1 May 2019, Pages 683-684 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty:

The BIN1 rs744373 SNP is associated with increased tau-PET levels and impaired memory

Posted on May 6, 2019

Nicolai Franzmeier, Anna Rubinski, Julia Neitzel, Michael Ewers & The Alzheimer’s Disease Neuroimaging Initiative (ADNI). Nature Communications, Volume 10, Issue 1, 1 December 2019, Article number 1766 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: , , ,

Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease

Posted on May 1, 2019

Deborah A. Roby, Fernanda Ruiz, Bailey A. Kermath, Jaymie R. Voorhees, Michael Niehoff, Jinsong Zhang, John E. Morley, Erik S. Musiek, Susan A. Farr , Thomas P. Burris. PLoS ONE, Volume 14, Issue 4, April 2019, Article number e0215004 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: ,

Experimental treatment could be ‘game-changing’ for genetic ALS, experts say

Posted on May 1, 2019

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Posted in: Clocks & Sleep, HPAN, Neurodegeneration, NeuroRestorative Therapy, News Faculty: