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CSF progranulin increases in the course of Alzheimer’s disease and is associated with sTREM2, neurodegeneration and cognitive decline

Posted on December 6, 2018

Marc Suárez‐Calvet, Anja Capell, Miguel Ángel Araque Caballero, Estrella Morenas‐Rodríguez, Katrin Fellerer, Nicolai Franzmeier, Gernot Kleinberger, Erden Eren, Yuetiva Deming, Laura Piccio, Celeste M Karch, Carlos Cruchaga, Katrina Paumier, Randall J Bateman, Anne M Fagan, John C Morris, Johannes Levin, Adrian Danek, Mathias Jucker, Colin L Masters, Martin N Rossor, John M Ringman, Leslie M Shaw, John Q Trojanowski, Michael Weiner, Michael Ewers, Christian Haass, the Dominantly Inherited Alzheimer Network, the Alzheimer’s Disease Neuroimaging Initiative. EMBO Molecular Medicine, 2018, Article number e9712 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , ,

The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer’s disease

Posted on December 6, 2018

Daniel Twohig, Elena Rodriguez-Vieitez, Sigrid B. Sando, Guro Berge, Camilla Lauridsen, Ina Møller, Gøril R. Grøntvedt, Geir Bråthen, Kalicharan Patra, Guojun Bu, Tammie L. S. Benzinger, Celeste M. Karch, Anne Fagan, John C. Morris, Randall J. Bateman, Agneta Nordberg, Linda R. White, Henrietta M. Nielsen and for the Dominantly Inherited Alzheimer Network (DIAN). Acta neuropathologica communications, Volume 6, Issue 1, 26 November 2018, Page 130 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , ,

Alzheimer’s researchers receive Chan Zuckerberg Initiative funding

Posted on December 5, 2018

Research aims to show how immune system may drive neurodegenerative diseases Read More

Posted in: Axon Injury & Repair, HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, News

Hemodynamic Impairment Measured by Positron-Emission Tomography Is Regionally Associated with Decreased Cortical Thickness in Moyamoya Phenomenon

Posted on December 4, 2018

J.J. Lee, J.S. Shimony, H. Jafri, A.R. Zazulia, R.G. Dacey, G.R. Zipfel and C.P. Derdeyn. AJNR. American journal of neuroradiology, Volume 39, Issue 11, 1 November 2018, Pages 2037-2044 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Neurovascular Injury & Repair, Publications Faculty: ,

A deep learning approach to automate refinement of somatic variant calling from cancer sequencing data

Posted on November 22, 2018

Benjamin J. Ainscough, Erica K. Barnell, Peter Ronning, Katie M. Campbell, Alex H. Wagner, Todd A. Fehniger, Gavin P. Dunn, Ravindra Uppaluri, Ramaswamy Govindan, Thomas E. Rohan, Malachi Griffith, Elaine R. Mardis, S. Joshua Swamidass & Obi L. Griffith. Nature Genetics 2018 Read More

Posted in: Neurogenetics & Transcriptomics, NeuroRestorative Therapy, Publications Faculty: