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The Trem2 R47H Alzheimer’s risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans

Posted on September 24, 2018

Xianyuan Xiang, Thomas M. Piers, Benedikt Wefers, Kaichuan Zhu, Anna Mallach, Bettina Brunner, Gernot Kleinberger, Wilbur Song, Marco Colonna, Jochen Herms, Wolfgang Wurst, Jennifer M. Pocock and Christian Haass. Molecular Neurodegeneration, Volume 13, Issue 1, 6 September 2018, Article number 49 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty:

Inferring dynamic topology for decoding spatiotemporal structures in complex heterogeneous networks

Posted on September 20, 2018

Shuo Wang, Erik D. Herzog, István Z. Kiss, William J. Schwartz, Guy Bloch, Michael Sebek, Daniel Granados-Fuentes, Liang Wang, and Jr-Shin Li. Proceedings of the National Academy of Sciences of the United States of America, Volume 115, Issue 37, 11 September 2018, Pages 9300-9305 Read More

Posted in: Clocks & Sleep, Neurogenetics & Transcriptomics, Publications Faculty:

Regionally specific TSC1 and TSC2 gene expression in tuberous sclerosis complex

Posted on September 19, 2018

Yi Li, Matthew J. Barkovich, Celeste M. Karch, … Leo P. Sugrue. Scientific Reports, Volume 8, Issue 1, 1 December 2018, Article number 13373 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty:

Hepatic mitochondrial adaptations to physical activity: impact of sexual dimorphism, PGC1α and BNIP3-mediated mitophagy

Posted on September 18, 2018

Alex Von Schulze, Colin S. McCoin, Chiemela Onyekere, Julie Allen, Paige Geiger, Gerald W. Dorn II,E. Matthew Morris, John P. Thyfault. Journal of Physiology First published: 31 July 2018 Read More

Posted in: Neurogenetics & Transcriptomics, Publications Faculty:

Clinical predictors of extrapyramidal symptoms associated with aripiprazole augmentation for the treatment of late-life depression in a randomized controlled trial

Posted on September 14, 2018

Jonathan H. Hsu, Benoit H. Mulsant, Eric J. Lenze, Marcos Sanches, Jordan F. Karp, Charles F. Reynolds, III, and Daniel M. Blumberger. Journal of Clinical Psychiatry, Volume 79, Issue 4, July-August 2018, Article number 17m11764 Read More

Posted in: Neurogenetics & Transcriptomics, NeuroRestorative Therapy, Publications Faculty: