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HPAN

Genes linked to Alzheimer’s risk, resilience ID’d

Posted on August 21, 2019

Genes in the brain’s immune cells may point to strategy to protect against the disease Read More

Posted in: Axon Injury & Repair, HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, News Faculty: , ,

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk

Posted on August 21, 2019

Yuetiva Deming, Fabia Filipello, Francesca Cignarella, Claudia Cantoni, Simon Hsu, Robert Mikesell, Zeran Li, Jorge L Del-Aguila, Umber Dube, Fabiana Geraldo Farias, Joseph Bradley, John Budde, Laura Ibanez, Maria Victoria Fernandez, Kaj Blennow, Henrik Zetterberg, Amanda Heslegrave, Per M Johansson, Johan Svensson, Bengt Nellgård, Alberto Lleo, Daniel Alcolea, Jordi Clarimon, Lorena Rami, José Luis Molinuevo, Marc Suárez-Calvet, Estrella Morenas-Rodríguez, Gernot Kleinberger, Michael Ewers, Oscar Harari, Christian Haass, Thomas J Brett, Bruno A. Benitez, Celeste M. Karch, Laura Piccio and Carlos Cruchaga. Science Translational Medicine, Vol 11, Issue 505,14 August 2019 Read More

Posted in: Axon Injury & Repair, HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , ,

High-precision plasma β-amyloid 42/40 predicts current and future brain amyloidosis

Posted on August 5, 2019

Suzanne E. Schindler, James G. Bollinger, Vitaliy Ovod, Kwasi G. Mawuenyega, Yan Li, Brian A. Gordon, David M. Holtzman, John C. Morris, Tammie L.S. Benzinger, Chengjie Xiong, Anne M. Fagan, Randall J. Bateman. Neurology 2019 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , ,

A Blood Test for Alzheimer’s? It’s Coming, Scientists Report

Posted on August 2, 2019

A test that measures beta amyloid protein in the blood is more accurate than a brain scan and may indicate trouble years earlier. Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, News Faculty: ,

Desmin forms toxic, seeding-competent amyloid aggregates that persist in muscle fibers

Posted on August 2, 2019

Niraja Kedia, Khalid Arhzaouy, Sara K. Pittman, Yuanzi Sun, Mark Batchelor, Conrad C. Weihl, and Jan Bieschke. PNAS first published August 1, 2019 Read More

Posted in: HPAN, Neurodegeneration, Pilot Projects, Publications Faculty: