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HPAN

Estimating prevalence for limb-girdle muscular dystrophy based on public sequencing databases

Posted on June 12, 2019

Wei Liu, Sander Pajusalu, Nicole J. Lake, Geyu Zhou, Nilah Ioannidis, Plavi Mittal, Nicholas E. Johnson, Conrad C. Weihl, Bradley A. Williams, Douglas E. Albrecht, Laura E. Rufibach & Monkol Lek. Genetics in Medicine 2019 Read More

Posted in: HPAN, Neurodegeneration Faculty:

Simple nutrients bypass the requirement for HLH-30 in coupling lysosomal nutrient sensing to survival

Posted on June 11, 2019

John T. Murphy , Haiyan Liu , Xiucui Ma, Alex Shaver, Brian M. Egan, Clara Oh, Alexander Boyko, Travis Mazer, Samuel Ang, Rohan Khopkar, Ali Javaheri, Sandeep Kumar, Xuntian Jiang, Daniel Ory, Kartik Mani, Scot J. Matkovich, Kerry Kornfeld , Abhinav Diwan. PLoS biology, Volume 17, Issue 5, 1 May 2019, Page e3000245 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Publications Faculty:

miRNA contributions to pediatric-onset multiple sclerosis inferred from GWAS

Posted on June 7, 2019

Brooke Rhead, Xiaorong Shao, Jennifer S. Graves, Tanuja Chitnis, Amy T. Waldman, Timothy Lotze, Teri Schreiner, Anita Belman, Lauren Krupp, Benjamin M. Greenberg, Bianca Weinstock–Guttman, Gregory Aaen, Jan M. Tillema, Moses Rodriguez, Janace Hart, Stacy Caillier, Jayne Ness, Yolanda Harris, Jennifer Rubin, Meghan S. Candee, Mark Gorman, Leslie Benson, Soe Mar, Ilana Kahn, John Rose, T. Charles Casper, Hong Quach, Diana Quach, Catherine Schaefer, Emmanuelle Waubant, Lisa F. Barcellos on behalf of the US Network of Pediatric MS Centers. Annals of Clinical and Translational Neurology 2019 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty:

Aβ34 is a BACE1-derived degradation intermediate associated with amyloid clearance and Alzheimer’s disease progression

Posted on June 5, 2019

Filip Liebsch, Luka Kulic, Charlotte Teunissen, Adeola Shobo, Irem Ulku, Vivienne Engelschalt, Mark A. Hancock, Wiesje M. van der Flier, Peter Kunach, Pedro Rosa-Neto, Philip Scheltens, Judes Poirier, Paul Saftig, Randall J. Bateman, John Breitner, Christoph Hock & Gerhard Multhaup. Nature Communications, Volume 10, Issue 1, 1 December 2019, Article number 2240 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty:

Aminophospholipids are signal-transducing TREM2 ligands on apoptotic cells

Posted on June 1, 2019

Keiro Shirotani, Yuma Hori, Ryohei Yoshizaki, Eri Higuchi, Marco Colonna, Takashi Saito, Shoko Hashimoto, Takashi Saito, Takaomi C. Saido & Nobuhisa Iwata . Scientific Reports, Volume 9, Issue 1, 1 December 2019, Article number 7508 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: