Andrew Nguyen, PhD

Assistant Professor of Medicine, Saint Louis University

Strategies for increasing progranulin levels as potential therapies for progranulin-deficient FTD Read More

Email: andy.d.nguyen@health.slu.edu
Lab Phone: (314) 977-6186
Website: Nguyen lab
Lab Location: Doisy Hall, Room R205 (1402 South Grand Blvd)

Strategies for increasing progranulin levels as potential therapies for progranulin-deficient FTD

Our lab studies progranulin – a protein linked to frontotemporal dementia (FTD) – and how its deficiency causes neurodegeneration. We are currently testing strategies (including antisense oligonucleotides) for increasing progranulin levels as potential therapies for progranulin-deficient FTD. We are also investigating progranulin’s structure and function using a variety of molecular and cellular approaches. Our research program is very much aligned with the Hope Center’s mission to improve the lives of people living with neurological disorders, through collaborative research that aims to discover fundamental mechanisms of neurodegeneration and repair, and translate that new understanding into cures and treatments.

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