Engineering peripheral nerve repair

Marquardt, L.M., Sakiyama-Elbert, S.E.; (2013) Current Opinion in Biotechnology Read More

Abstract

Current approaches for treating peripheral nerve injury have resulted in promising, yet insufficient functional recovery compared to the clinical standard of care, autologous nerve grafts. In order to design a construct that can match the regenerative potential of the autograft, all facets of nerve tissue must be incorporated in a combinatorial therapy. Engineered biomaterial scaffolds in the future will have to promote enhanced regeneration and appropriate reinnervation by targeting the highly sensitive response of regenerating nerves to their surrounding microenvironment. © 2013 Elsevier Ltd. All rights reserved.

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Posted on June 28, 2013
Posted in: Axon Injury & Repair, Publications Authors: