Graphene-based contrast agents for photoacoustic and thermoacoustic tomography

Lalwani G, Cai X, Nie L, Wang LV, Sitharaman B; (2013) Photoacoustics, 1 (3-4), pp. 62-67 Read More

Abstract

In this work, graphene nanoribbons and nanoplatelets were investigated as contrast agents for photoacoustic and thermoacoustic tomography (PAT and TAT). We show that oxidized single- and multi-walled graphene oxide nanoribbons (O-SWGNRs, O-MWGNRs) exhibit approximately 5-10 fold signal enhancement for PAT in comparison to blood at the wavelength of 755. nm, and approximately 10-28% signal enhancement for TAT in comparison to deionized (DI) water at 3. GHz. Oxidized graphite microparticles (O-GMPs) and exfoliated graphene oxide nanoplatelets (O-GNPs) show no significant signal enhancement for PAT, and approximately 12-29% signal enhancement for TAT. These results indicate that O-GNRs show promise as multi-modal PAT and TAT contrast agents, and that O-GNPs are suitable contrast agents for TAT.

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Posted on December 16, 2013
Posted in: Neurovascular Injury & Repair, Publications Authors: