Multifocal stroke with proliferation of small cerebral arteries in hepatopulmonary syndrome

John R. Younce, DeWitte T. Cross, Manu S. Goyal, Jin-Moo Lee. Neurology: Clinical Practice, Volume 8, Issue 3, 1 June 2018, Pages e15-e17 Read More


Cirrhosis of the liver has been linked to several changes in risk of cerebrovascular disease and may increase the risk of hemorrhage while reducing the risk of ischemic stroke. 1,2 The pathophysiology underlying these changes remains unclear, though intracranial hemorrhage and vascular malformations related to liver disease have been described. 1,3 Cirrhosis may be complicated by hepatopulmonary syndrome (HPS), in which distal pulmonary arteries dilate, become tortuous, produce shunt physiology, and often produce arteriovenous (AV) malformations. 4. © © 2018 American Academy of Neurology.

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Posted on October 16, 2018
Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Authors: