Mechanism behind heartbeat regulation, heart function uncovered

New findings show how CaM and PIP2 orchestrate large-scale molecular movement of the KCNQ1 cytoplasmic domain to facilitate channel opening Read More

From the WashU Newsroom

Jianmin Cui, PhD, professor of biomedical engineering at the McKelvey School of Engineering, and Po wei (Billy) Kang, an MD/PhD student at the School of Medicine who conducts research in Cui’s lab, led an international team that revealed new details on how two biomolecules modulate opening and closing of the KCNQ1 potassium channel. This channel is important for proper heart function and regulating heartbeat, which ranges from about 60-100 beats per minute in a normal adult.

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Posted on February 5, 2021
Posted in: Neurogenetics & Transcriptomics, News Authors: