Lysosome Processing & Transport

Organizers: Bruno Benitez and Carlos Cruchaga Read More


The Lysosome Processing & Transport Group is a group of investigators whose research goals range from basic lysosomal system biology to therapy in model organisms and humans. The focus of this group is to introduce key research developments and current innovative studies in the lysosome field.  Members of this group share an interest in the autophagy/lysosomal pathway (ALP) and its relationship to neurodegenerative disorders, development of novel therapeutic strategies of Lysosome storage diseases and the use of cell and animal models as tools to determine the role of the ALP in the pathogenesis of neurological and cardiovascular diseases.  Group meetings are open to the Washington University community, and those outside also are welcome to present their work and exchange new data and cutting-edge ideas.

Organizers/Contact Information

For additional information about the Lysosome Processing & Transport Group, please contact the organizers Bruno Benitez or Carlos Cruchaga, or our administrative coordinator, Jan Konrad.

2016/2017 Schedule, Lysosome Processing & Transport Group

Every other month on the 3rd Thursday
BJC Institute of Health 9AB

  • September 15, 2016: Terra Barnes (Holy Lab, WashU Neuroscience), “An Animal Model of Stuttering”
  • October 20, 2016: Leah Czerniewski (Lee Lab, WashU Neurology), “Tracking De Novo Aβ Generation In Live Cells Using Unnatural Amino Acids and FluorogenicClick Chemistry”
  • December 15, 2016: Lin Liu (Kornfeld Lab, WashU Medicine), “Method for Producing Highly Phosphorylated Lysosomal Enzymes for Enzyme Replacement Therapy”
  • February 16, 2017: Sergin Ismail (Razani Lab, WashU Medicine), “Building a Better Macrophage to Treat Atherosclerosis”
  • April 20, 2017: Eugene Lee (Weihl Lab, WashU Neurology), “Better Call Sequestosome1: the role of p62/SQSTM1 in aggrephagy”
  • June 15, 2017: OPEN
  • August 17, 2017: Ali Javaheri (Diwan Lab, WashU Medicine)
  • October 19, 2017: Leah Czerniewski (Lee Lab, WashU Neurology)
  • December 21, 2017: Anil Cashikar (WashU Cell Biology & Physiology)

All meetings are listed on the Neuroscience Calendar of the Office of Neuroscience Research.

Archive of Previous Seasons


Lysosome Processing & Transport Faculty

Faculty organizers: Bruno Benitez, Carlos Cruchaga

Affiliated faculty

Bruno Benitez (WashU Medicine)
Carlos Cruchaga (WashU Psychiatry)
Scott Crick (WashU Neurology)
Abhinav Diwan (WashU Medicine)
Phyllis Hanson (WashU Cell Biology & Physiology)
Timothy Holy (WashU Neuroscience)
Celeste Karch (WashU Psychiatry)
Stuart Kornfeld (WashU Medicine)
Jin-Moo Lee (WashU Neurology)
Adriana Montano (St. Louis University)
Daniel Ory (WashU Medicine)
Mark Sands (WashU Medicine)