Axon Injury & Repair Group

2022/2023 Schedule

Organizer: Valeria Cavalli

  • October 4, 2022: Mark Rutherford (WashU Otolaryngology) “Selective glutamate receptor antagonism suppresses excitotoxicity in cochlear nerve fibers to prevent effects of noise trauma while maintaining hearing function”
  • November 1, 2022: Vishnu Muraleedharan Saraswathy (Mokalled lab, WashU Developmental Biology) “Single-cell transcriptomics reveal potent pro-regenerative populations in the adult spinal cord”
  • December 6, 2022: Xiaoying Chen (Holtzman lab, WashU Neurology) “Neuro-immune Interactions in Healthy and Diseased Brain”
  • January 3, 2023: Rui Feng (Cavalli lab, WashU Neuroscience) “Antagonizing Endothelin B receptor in satellite glial cells improves nerve regeneration and aging-dependent neuronal regenerative decline”
  • February 7, 2023: Jesús Acevedo Cintron (Wood and Mackinnon labs, WashU Surgery) “Modification of the inflammatory microenvironment in Acellular Nerve Allografts repairing nerve gaps”
  • March 14, 2023: Sean McCracken, Allison Hall (Williams lab, WashU Ophthalmology & Visual Sciences)
    • Sean McCracken“Homeostatic Ca2+ levels predict retinal ganglion cell susceptibility to axon damage”
    • Allison Hall: “Investigating the regenerative potential of a novel retinal ganglion cell type”
  • June 6, 2023: Stefanie Geisler (WashU Neurology) – “DRG response in Bortezomib-induced neuropathy”
2021/2022 Schedule

Organizer: Valeria Cavalli

  • October 5, 2021: Valeria Cavalli (WashU Dept. of Neuroscience) “Satellite Glial cells in sensory nervous system health and disease”
  • November 2, 2021: Mayssa Mokalled (WashU Developmental Biology) “Fishing for spinal cord regeneration mechanisms”
  • December 7, 2021: Junwei Du, Igor Luzhansky (Berezin lab, WashU Radiology)
    • Junwei Du – “Exploring mechanisms of oxaliplatin-induced peripheral neuropathy in mice”
    • Igor Luzhansky – “Visualizing peripheral nerve regeneration in vivo”
  • January 4, 2022: Bryan Copits (WashU Anesthesiology) “Synaptic adhesion molecules and somatosensory circuit (re)assembly”
  • February 1, 2022: Jesús Acevedo Cintron (Wood and Mackinnon labs, WashU Surgery) “The role of the inflammatory microenvironment in Acellular Nerve Allografts repairing nerve gaps”
  • March 1, 2022: Philip Williams (WashU Ophthalmology & Visual Sciences) “Cellular traits linked with survival following axon injury in retinal ganglion cells”
  • March 29, 2022: Kelsey Krus (DiAntonio lab, WashU Developmental Biology) “Loss of Stathmin-2, a hallmark of TDP-43-associated ALS, causes motor neuropathy”
  • May 3, 2022: Stefanie Geisler (WashU Neurology) “Bortezomib-induced neuropathy – new insights into mechanisms”
2020/2021 Schedule

Organizer: Valeria Cavalli

  • November 10, 2020: Mayssa Mokalled (WashU Developmental Biology) “Spinal cord injury: From basic mechanisms to regenerative therapies”
  • December 1, 2020: Philip Williams (WashU Ophthalmology & Visual Sciences) “The role of activity in retinal ganglion cell survival and axon regeneration”
  • February 2, 2021: Matthew Figley (DiAntonio lab, WashU Developmental Biology) “A mechanism of metabolic sensing by SARM1 to trigger axon degeneration”
  • March 2, 2021: Valeria Cavalli (WashU Dept. of Neuroscience) “Neuronal, glial and immune mechanisms promoting axon regeneration”
  • May 4, 2021: Scheller lab (WashU Medicine)
    • Jennifer Brazill: “A Sarm and a leg: balancing the costs of peripheral complications in diabetic bone disease”
    • David Shin: “TSC2 KO in Nav1.8+ nociceptors dissociates gains in body mass from high fat diet-induced changes in bone and metabolic health”
2019/2020 Schedule

Organizer: Valeria Cavalli

  • October 8, 2019: Oshri Avraham (Cavalli lab, WashU Dept. of Neuroscience) “Fatty acid synthesis in satellite glial cell promotes regenerative growth in sensory neurons”
  • November 5, 2019: Stephanie Geisler (WashU Neurology) “Chemotherapy-induced neuropathy: From mechanisms to therapies”
  • December 3, 2019: Aaron DiAntonio (WashU Developmental Biology) “The SARM1 Axon Degeneration Pathway: New Links to Neuroinflammation, Necroptosis, and Signal Transduction”
  • January 7, 2020: Deng Pan (Wood lab, WashU Surgery) “Role of inflammation in regeneration of acellular nerve allograft repaired peripheral nerve”
  • February 4, 2020: Allison Soung (Klein lab, WashU Medicine) “Astrocyte responses via IL-1 regulate recovery from West Nile virus encephalitis”
  • CANCELLED – March 24, 2020: Mokalled lab (WashU Developmental Biology)
  • CANCELLED – April 7, 2020: Philip Williams (WashU Ophthalmology & Visual Sciences)
  • CANCELLED – May 5, 2020: Nikhil Chandra (Moran lab, WashU Biomedical Engineering and Ray/MacEwan lab, WashU Neurosurgery)