The latest published manuscripts and reviews from Hope Center investigators, and publications based on use of Hope Center Cores. Click on titles to learn more. Read More

Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening

Posted on November 15, 2017

Chao Wang, Michael E. Ward, Robert Chen, Kai Liu, Tara E. Tracy, Xu Chen, Min Xie, Peter Dongmin Sohn, Connor Ludwig, Anke Meyer-Franke, Celeste M. Karch, Sheng Ding, Li Gan: Stem Cell Reports, Volume 9, Issue 4, 10 October 2017, Pages 1221-1233 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty:

Evaluation of 64Cu-Based Radiopharmaceuticals that Target Aβ Peptide Aggregates as Diagnostic Tools for Alzheimer’s Disease

Posted on November 14, 2017

Nilantha Bandara, Anuj K. Sharma, Stephanie Krieger, Jason W. Schultz, Byung Hee Han, Buck E. Rogers, and Liviu M. Mirica: Journal of the American Chemical Society, Volume 139, Issue 36, 2017, Pages 12550-12558 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

On the Stability of BOLD fMRI Correlations

Posted on November 14, 2017

Timothy O. Laumann, Abraham Z. Snyder, Anish Mitra, Evan M. Gordon, Caterina Gratton, Babatunde Adeyemo, Adrian W. Gilmore, Steven M. Nelson, Jeff J. Berg, Deanna J. Greene, John E. McCarthy, Enzo Tagliazucchi, Helmut Laufs, Bradley L. Schlaggar, Nico U. F. Dosenbach, Steven E. Petersen: Cerebral Cortex, Volume 27, Issue 10, 1 October 2017, Pages 4719-4732 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Neurovascular Injury & Repair, Publications Faculty: , ,

Functionally distinct tendons from elastin haploinsufficient mice exhibit mild stiffening and tendon-specific structural alteration

Posted on November 13, 2017

Jeremy D. Eekhoff, Fei Fang, Lindsey G. Kahan, Gabriela Espinosa, Austin J. Cocciolone, Jessica E. Wagenseil, Robert P. Mecham and Spencer P. Lake: Journal of Biomechanical Engineering, Volume 139, Issue 11, 1 November 2017, Article number 111003 Read More

Posted in: Neurovascular Injury & Repair, Publications Faculty:

The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition

Posted on November 13, 2017

Ghazaleh Eskandari-Sedighi, Nathalie Daude, Hristina Gapeshina, David W. Sanders, Razieh Kamali-Jamil, Jing Yang, Beipei Shi, Holger Wille, Bernardino Ghetti, Marc I. Diamond, Christopher Janus and David Westaway: Molecular Neurodegeneration, Volume 12, Issue 1, 4 October 2017, Article number 72 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: