The latest published manuscripts and reviews from Hope Center investigators, and publications based on use of Hope Center Cores. Click on titles to learn more. Read More

Common binding sites for cholesterol and neurosteroids on a pentameric ligand-gated ion channel

Posted on December 10, 2018

Melissa M. Budelier, Wayland W.L. Cheng, Zi-Wei Chen, John R. Bracamontes, Yusuke Sugasawa, Kathiresan Krishnan, Laurel Mydock-McGrane, Douglas F. Covey, Alex S. Evers. Biochimica et Biophysica Acta – Molecular and Cell Biology of Lipids, Volume 1864, Issue 2, February 2019, Pages 128-136 Read More

Posted in: Axon Injury & Repair, Publications Faculty:

CSF progranulin increases in the course of Alzheimer’s disease and is associated with sTREM2, neurodegeneration and cognitive decline

Posted on December 6, 2018

Marc Suárez‐Calvet, Anja Capell, Miguel Ángel Araque Caballero, Estrella Morenas‐Rodríguez, Katrin Fellerer, Nicolai Franzmeier, Gernot Kleinberger, Erden Eren, Yuetiva Deming, Laura Piccio, Celeste M Karch, Carlos Cruchaga, Katrina Paumier, Randall J Bateman, Anne M Fagan, John C Morris, Johannes Levin, Adrian Danek, Mathias Jucker, Colin L Masters, Martin N Rossor, John M Ringman, Leslie M Shaw, John Q Trojanowski, Michael Weiner, Michael Ewers, Christian Haass, the Dominantly Inherited Alzheimer Network, the Alzheimer’s Disease Neuroimaging Initiative. EMBO Molecular Medicine, 2018, Article number e9712 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , ,

Depression and Alzheimer’s Disease Biomarkers Predict Driving Decline

Posted on December 6, 2018

Babulal, Ganesh M.; Chen, Suziek; Williams, Monique M.; Trani, Jean-Francois; Bakhshi, Parul; Chao, Grace L.; Stout, Sarah H.; Fagan, Anne M.; Benzinger, Tammie L.S.; Holtzman, David M.; Morris, John C.; Roe, Catherine M.. Journal of Alzheimer’s Disease, Volume 66, Issue 3, 2018, Pages 1213-1221 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: , ,

Understanding disease progression and improving Alzheimer’s disease clinical trials: Recent highlights from the Alzheimer’s Disease Neuroimaging Initiative

Posted on December 6, 2018

Dallas P. Veitch, Michael W. Weiner, Paul S. Aisen, Laurel A. Beckett, Nigel J. Cairns, Robert C. Green, Danielle Harvey, Clifford R. Jack Jr., William Jagust, John C. Morris, Ronald C. Petersen, Andrew J. Saykin, Leslie M. Shaw, Arthur W. Toga, John Q. Trojanowski, Alzheimer’s Disease Neuroimaging Initiative. Alzheimer’s and Dementia 2018 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

The relevance of cerebrospinal fluid α-synuclein levels to sporadic and familial Alzheimer’s disease

Posted on December 6, 2018

Daniel Twohig, Elena Rodriguez-Vieitez, Sigrid B. Sando, Guro Berge, Camilla Lauridsen, Ina Møller, Gøril R. Grøntvedt, Geir Bråthen, Kalicharan Patra, Guojun Bu, Tammie L. S. Benzinger, Celeste M. Karch, Anne Fagan, John C. Morris, Randall J. Bateman, Agneta Nordberg, Linda R. White, Henrietta M. Nielsen and for the Dominantly Inherited Alzheimer Network (DIAN). Acta neuropathologica communications, Volume 6, Issue 1, 26 November 2018, Page 130 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , ,