Protein Aggregation & Neurodegeneration

Working group for HPAN
Organizer: Chris Weihl Read More


The Protein Aggregation & Neurodegeneration Research Group is the working group for the Hope Center Program on Protein Aggregation & Neurodegeneration (HPAN), the most formalized of the Hope Center Research groups. HPAN’s goal is to develop better ways to diagnose and treat neurodegenerative diseases through an understanding of the underlying molecular mechanisms that lead to protein aggregation and disease. Group meetings are in two different formats, a lab meeting and a PI chalk talk (PIs only), and are open to investigators in the Washington University community.

All meetings are listed on the ONR Calendar of the Office of Neuroscience Research.

Organizer/Contact Information

For additional information about Protein Aggregation & Neurodegeneration Group Meetings, please contact the faculty organizer Chris Weihl or the administrative coordinator, Kally Coleman.

2021/2022 Schedule, Protein Aggregation & Neurodegeneration Group

2nd Wednesday of the month
8:30a – 9:30a
Zoom conference

For virtual meeting information email the Hope Center.

  • October 13: Dong-oh Seo (Holtzman lab, WashU Neurology) “Evidence that the gut microbiota regulates progression of neurodegeneration in a mouse model of tauopathy”
  • November 10: Brian Gordon (WashU Radiology) “Influence of APOE ε4 genotype and amyloid-β on tau in regions of high APOE mRNA expression”
  • December 8: Michio Inoue (Weihl lab, WashU Neurology) “Mutations in DNAJB4 define a novel chaperonopathy”
  • January 12: Hunter Patterson (Miller lab, WashU Neurology) “miRNAs in Moderation: Pleiotropic Effects of miR-146a in ALS”
  • February 9: Andrew Yoo (WashU Developmental Biology) “Modeling human neurodegeneration by direct neuronal reprogramming”
  • March 9: Andrea Francesca Salvador (Kipnis lab, WashU Pathology & Immunology) “The cellular and transcriptomic responses in the injured spinal cord are altered in aging”
  • April 13: Moydul Islam (Diwan lab, WashU Medicine) “Altered Phase Separation Characteristics of CRYAB, a Cardiac-enriched Chaperone, Provokes Proteotoxicity in Ischemic Cardiomyopathy”
  • HYBRID* – May 11: Charisse Winston-Gray (University of California, San Diego) “Biomarker and Pathogenic Potential of Blood-Based Exosomes in Alzheimer’s Disease”
    *In-person location: Knight ADRC Building, Room 378 (4488 Forest Park, Medical Campus)

For previous years’ talks, check out the archive links below.

All meetings are listed on the ONR Calendar of the Office of Neuroscience Research.

Archives of previous seasons












Protein Aggregation & Neurodegeneration Faculty Members

Group meeting faculty organizer: Chris Weihl (WashU Neurology)

Affiliated faculty members

Beau Ances (WashU Neurology)
Yuna Ayala (St. Louis University)
Randall Bateman (WashU Neurology)
Kendall Blumer (WashU Cell Biology & Physiology)
Thomas Brett (WashU Medicine)
Thomas Burris (St. Louis College of Pharmacy/WashU Anesthesiology)
Anil Cashikar (WashU Psychiatry)
Zhou-Feng Chen (WashU Anesthesiology)
John Cirrito (WashU Neurology)
Marco Colonna (WashU Pathology & Immunology)
Carlos Cruchaga (WashU Psychiatry)
Gus Davis (WashU Neurology)
Marc Diamond (WashU Neurology)
Abhinav Diwan (WashU Medicine)
Anne Fagan (WashU Neurology)
Carl Frieden (WashU Biochemistry & Molecular Biophysics)
Gilbert Gallardo (WashU Neurology)
Dennis Hallahan (WashU Radiation Oncology)
Edward Han (WashU Neuroscience)
Tamara Hershey (WashU Psychiatry)
Didier Hodzic (WashU Developmental Biology)
David Holtzman (WashU Neurology)
Meredith Jackrel (WashU Chemistry)
Sanjay Jain (WashU Medicine)
Celeste Karch (WashU Psychiatry)
Jonathan Kipnis (WashU Pathology & Immunology)
Paul Kotzbauer (WashU Neurology)
Geraldine Kress (WashU Neurology)
Jin-Moo Lee (WashU Neurology)
Mingjie Li (WashU Neurology)
David Limbrick (WashU Neurosurgery)
Brendan Lucey (WashU Neurology)
Moe Mahjoub (WashU Medicine)
Soe Soe Mar (WashU Neurology)
Helen McNeill (WashU Developmental Biology)
Steve Mennerick (WashU Psychiatry)
Tim Miller (WashU Neurology)
Liviu Mirica (WashU Chemistry)
John Morris (WashU Neurology)
Erik Musiek (WashU Neurology)
Andrew Nguyen (Saint Louis University)
David Ornitz (WashU Developmental Biology)
Dan Ory (WashU Medicine)
Rohit Pappu (WashU Biomedical Engineering)
Steven Paul (WashU Psychiatry)
David Perlmutter (WashU Pediatrics)
Joel Perlmutter (WashU Neurology)
Richard Perrin (WashU Pathology & Immunology)
Alan Pestronk (WashU Neurology)
Steve Petersen (WashU Neurology)
Marc Raichle (WashU Radiology)
Naresha Saligrama (WashU Neurology)
Daniela Salvemini (Saint Louis University)
Mark Sands (WashU Medicine)
Robert Schmidt (WashU Pathology & Immunology)
Joy Snider (WashU Neurology)
Amber Stratman (WashU Cell Biology & Physiology)
Heather True (WashU Cell Biology & Physiology)
Fumihiko Urano (WashU Medicine)
Andrei Vlassenko (WashU Radiology)
Yong Wang (WashU Radiology)
Chris Weihl (WashU Neurology)
David Wozniak (WashU Psychiatry)
Hiroko Yano (WashU Neurosurgery)
Andrew Yoo (WashU Developmental Biology)
Greg Zipfel (WashU Neurosurgery)