Working group for HPAN
Organizer: Chris Weihl Read More


The Neurodegeneration Research Group is the working group for the Hope Center Program on Protein Aggregation & Neurodegeneration (HPAN), the most formalized of the Hope Center Research groups. HPAN’s goal is to develop better ways to diagnose and treat neurodegenerative diseases through an understanding of the underlying molecular mechanisms that lead to protein aggregation and disease. Group meetings are in two different formats, a lab meeting and a PI chalk talk (PIs only), and are open to investigators in the Washington University community.

All meetings are listed on the Neuroscience Calendar of the Office of Neuroscience Research.

Organizer/Contact Information

For additional information about Neurodegeneration Lab Meetings or Neurodegeneration PI Chalk Talks, please contact the organizer Chris Weihl or the administrative coordinator, Jan Konrad.

2013/2014 Schedule, Protein Aggregation & Neurodegeneration Group

2nd Wednesday of the month
8:30a – 9:30a
Farrell 214*
*Note that all meetings in the spring have been moved to BJC Institute of Health 9AB.

  • September 11: Celeste Karch (WUSTL Psychiatry), “The molecular mechanisms underlying phospholipase D3 as a risk factor for Alzheimer’s disease”
  • October 9: Kaoru Yamada (Holtzman Lab, WUSTL Neurology), “Neuronal activity regulates extracellular tau in vivo”
  • November 13: Jan Bieschke (WUSTL Biomedical Engineering), “Molecular mechanisms of neuronal Abeta uptake”
  • December 11: Mike Vasek (Klein Lab, WUSTL Internal Medicine), “West Nile virus encephalitis: A one, two, three knockout punch to the hippocampus”
  • January  8: Kevin Stein (True Lab, WUSTL Cell Biology & Physiology), Chris Weihl (WUSTL Neurology), “Myopathy-Causing Mutations in an Hsp40 Chaperone Disrupt Interactions with Specific Client-Conformers”"
  • February 12: Marc Diamond (WUSTL Neurology)
  • March 12: Dan Ory (WUSTL Internal Medicine), “Proteostasis regulation for treatment of Niemann-Pick C1 disease”
  • April 9: Rohit Pappu (WUSTL Biomedical Engineering)
  • May 14: Matt Crisp (Miller Lab, WUSTL Neurology), “Stable isotope labeling kinetics reveal tissue-specific differences in SOD1 turnover in an ALS animal model”

All meetings are listed on the Neuroscience Calendar of the Office of Neuroscience Research.

Archives of previous seasons




Protein Aggregation & Neurodegeneration Faculty

Group meeting faculty organizer: Chris Weihl

Affiliated faculty

Beau Ances (WUSTL Neurology)
Yuna Ayala (St. Louis University)
Randall Bateman (WUSTL Neurology)
Jan Bieschke (WUSTL Biomedical Engineering)
Kendall Blumer (WUSTL Cell Biology & Physiology)
David Brody (WUSTL Neurology)
Nigel Cairns (WUSTL Neurology)
Zhou-Feng Chen (WUSTL Anesthesiology)
John Cirrito (WUSTL Neurology)
Michael Crowder (WUSTL Anesthesiology)
Carlos Cruchaga (WUSTL Psychiatry)
Adish Dani (WUSTL Pathology & Immunology)
Marc Diamond (WUSTL Neurology)
Hans Dietrich (WUSTL Neurosurgery)
Anne Fagan (WUSTL Neurology)
Simon Fisher (WUSTL Internal Medicine)
Carl Frieden (WUSTL Biochemistry & Molecular Biophysics)
Jeff Gidday (WUSTL Neurosurgery)
Alison Goate (WUSTL Psychiatry)
Dennis Hallahan (WUSTL Radiation Oncology)
Henry Han (WUSTL Neurosurgery)
Phyllis Hanson (WUSTL Cell Biology & Physiology)
Tamara Hershey (WUSTL Psychiatry)
Robert Heuckeroth (WUSTL Pediatrics)
Didier Hodzic (WUSTL Ophthalmology & Visual Sciences)
David Holtzman (WUSTL Neurology)
Sanjay Jain (WUSTL Internal Medicine)
Celeste Karch (WUSTL Psychiatry)
Paul Kotzbauer (WUSTL Neurology)
Jin-Moo Lee (WUSTL Neurology)
Mingjie Li (WUSTL Neurology)
David Limbrick (WUSTL Neurosurgery)
Moe Mahjoub (WUSTL Internal Medicine)
Steve Mennerick (WUSTL Psychiatry)
Tim Miller (WUSTL Neurology)
Erik Musiek (WUSTL Neurology)
Dan Ory (WUSTL Internal Medicine)
Rohit Pappu (WUSTL Biomedical Engineering)
Joel Perlmutter (WUSTL Neurology)
Richard Perrin (WUSTL Pathology & Immunology)
Alan Pestronk (WUSTL Neurology)
Marc Raichle (WUSTL Radiology)
Mark Sands (WUSTL Internal Medicine)
Robert Schmidt (WUSTL Pathology & Immunology)
Joy Snider (WUSTL Neurology)
Heather True (WUSTL Cell Biology & Physiology)
Fumihiko Urano (WUSTL Internal Medicine)
Andrei Vlassenko (WUSTL Radiology)
Yong Wang (WUSTL Radiology)
Chris Weihl (WUSTL Neurology)
David Wozniak (WUSTL Psychiatry)
Qin Yang (WUSTL Radiation Oncology)
Hiroko Yano (WUSTL Neurosurgery)
Andrew Yoo (WUSTL Developmental Biology)
Greg Zipfel (WUSTL Neurosurgery)