2010/2011 Monday Noon Seminars

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November 29: Season kick-off

  • Alison Goate, “State of the Hope Center”
  • December 6: Jungsu Kim (WUSTL Neurology), “Role of LDLR in apoE and Abeta metabolism”
    Carlos Cruchaga (WUSTL Psychiatry), “Pathogenic Mutations in APP, PSEN1, PSEN2, GRN and MAPT in Families with Late Onset Alzheimer Disease”

Clinical Translation/Biomarkers mini-series

Organizers, Anne Fagan and Randall Bateman

  • January 1: Randall Bateman (WUSTL Neurology), “The Dominantly Inherited Alzheimer’s Disease Network Treatment Trials
  • January 10: Henry Han (WUSTL Neurosurgery), “Molecular probes for cerebrovascular-specific amyloid imaging”
  • January 24: Les Shaw (University of Pennsylvania) , “Early detection of Alzheimer’s disease: are CSF A-beta 1-42 and tau biomarker tests ready for the challenge?”
  • January 31: Beau Ances (WUSTL Neurology), “The Tie That Binds: The Role of Neuroimaging in Neurodegenerative Disorders”

Neurogenesis and Stem Cells mini-series

Organizers, Naren Ramanan and Josh Rubin

  • February 7: Craig Micchelli (WUSTL Developmental Biology), “Understanding Stem Cell Logic Using Molecular Genetics
  • February 14: Hongjun Song (Johns Hopkins University), “Molecular mechanisms regulating adult neural stem cells and neurogenesis”
  • February 21: David Gutmann (WUSTL Neurology), “Using Cancer to Study Normal Neural Stem Cell Function”
  • February 28: Kristen Kroll (WUSTL Developmental Biology), “Setting the epigenetic state during lineage commitment of embryonic stem cells”

Parkinson’s Disease mini-series

Organizers, Karen O’Malley and Paul Kotzbauer

  • March 7: Joel Perlmutter (WUSTL Neurology),“Parkinson’s disease: New insights into pathophysiology and the role of neuroimaging”
  • March 14: Karen O’Malley (WUSTL Anatomy & Neurobiology), “Why are dopamine neurons so vulnerable in Parkinson’s disease?”
  • March 21: Malu Tansey (Emory University), “Interplay between genetics and environment in Parkinson’s disease: two-hit neuroinflammation models of dopaminergic neuron death
  • March 28: Paul Kotzbauer (WUSTL Neurology), “Neurodegenerative Mechanisms in Hereditary Parkinsonism Caused by Mutations in the Alpha-Synuclein and PLA2G6 Genes”
  • April 4: Mark Cookson (National Institute on Aging), “Pathways to Parkinsonism”

ALS/FTD mini-series

Organizers, Tim Miller and Nigel Cairns

  • April 18: Bruce Miller (University of California, San Francisco), “Clinical links between FTD and ALS”
  • May 2: Bob Baloh (WUSTL Neurology), “Deciphering the role of RNA binding proteins in ALS and FTLD
  • May 9: Virginia Lee (University of Pennsylvania), “Clinical and Neuropathological Links Between FTD and ALS
  • May 16: Tim Miller (WUSTL Neurology), “Treatment of ALS and FTLD: Hope for the future?”
    Nigel Cairns (WUSTL Neurology), “Two sides of the same coin? Neuropathology and genetics of ALS and FTLD”