Active Pilot Projects

Pilot Project awards in 2020 and 2021 Read More

Patient-Specific Neuroimaging Markers of Recovery After Traumatic Brain Injury

2021 Award

Principal Investigator: Evan Gordon (WashU Radiology)
Collaborators: Nico Dosenbach, Terrance Kummer, Benjamin Kay (WashU Neurology)

Pilot Project Details

A model of human neuroprotection

2021 Award

Principal Investigator: Daniel Kerschensteiner (WashU Ophthalmology & Visual Sciences)
Collaborator: Philip Ruzycki (WashU Ophthalmology & Visual Sciences)

Pilot Project Details

Brain injury creates a supportive microenvironment for tumorigenesis

2021 Award

Principal Investigator: Terrance Kummer (WashU Neurology)
Collaborator: David Gutmann (WashU Neurology)

Pilot Project Details

Mapping ketamine-orchestrated translatome to rapid-acting anti-anhedonic effects at the synaptic level with cell-type specific resolution

2021 Award

Principal Investigator: Marco Pignatelli (WashU Psychiatry)
Collaborator: Vijay Samineni (WashU Anesthesiology)

Pilot Project Details

VEGFA as a potential therapeutic target to enhance motor recovery following acute and chronic nerve injury

2021 Award

Principal Investigator: Alison Snyder-Warwick (WashU Surgery)
Collaborators: Jianjun Guan ( WashU Mechanical Engineering & Materials Science)

Pilot Project Details

Role of satellite glia cells in chemotherapy-induced neuropathy

2020 Award

Principal Investigator: Stefanie Geisler (WashU Neurology)
Collaborator: Valeria Cavalli (WashU Dept. of Neuroscience)

Pilot Project Details

Microglial Phagocytosis as a Determinant of Neuro-inflammation in AD pathogenesis

2020 Award

Principal investigator: Abhinav Diwan (WashU Medicine)
Collaborators: Carolina Soriano Tarraga (WashU Psychiatry), Oscar Harari (WashU Psychiatry)

Pilot Project Details

Defining the molecular basis for inhibiting LRP1-mediated cellular propagation of pathogenic tau

2020 Award

Principal Investigator: Thomas Brett (WashU Medicine)
Collaborator: Gaya Amarasinghe (WashU Pathology & Immunology)

Pilot Project Details

A synthetic gene therapy approach for Angelman syndrome

2020 Award

Principal Investigator: Jason Yi (WashU Dept of Neuroscience)
Collaborator: Susan Maloney (WashU Psychiatry)

Pilot Project Details

Targeting DNMT3A as a therapeutic strategy for Huntington’s disease

2020 Award

Principal Investigator: Hiroko Yano (WashU Neurosurgery)
Collaborator: Andrew Yoo (WashU Developmental Biology), Allegra Petti (WashU Neurosurgery)

Pilot Project Details

Previous Pilot Awards

Hope Center Pilot awards are two-year projects.  Click below to learn details about past pilot projects.

Previous pilot awards