Role of satellite glia cells in chemotherapy-induced neuropathy
2020 Award
Principal Investigator: Stefanie Geisler (WashU Neurology)
Collaborator: Valeria Cavalli (WashU Dept. of Neuroscience)
Microglial Phagocytosis as a Determinant of Neuro-inflammation in AD pathogenesis
2020 Award
Principal investigator: Abhinav Diwan (WashU Medicine)
Collaborators: Carolina Soriano Tarraga (WashU Psychiatry), Oscar Harari (WashU Psychiatry)
Defining the molecular basis for inhibiting LRP1-mediated cellular propagation of pathogenic tau
2020 Award
Principal Investigator: Thomas Brett (WashU Medicine)
Collaborator: Gaya Amarasinghe (WashU Pathology & Immunology)
A synthetic gene therapy approach for Angelman syndrome
2020 Award
Principal Investigator: Jason Yi (WashU Dept of Neuroscience)
Collaborator: Susan Maloney (WashU Psychiatry)
Targeting DNMT3A as a therapeutic strategy for Huntington’s disease
2020 Award
Principal Investigator: Hiroko Yano (WashU Neurosurgery)
Collaborator: Andrew Yoo (WashU Developmental Biology), Allegra Petti (WashU Neurosurgery)
Determining the pathogenic role of FGFR3 autoantibodies in idiopathic small fiber neuropathy
2019 Award
Principal Investigator: Robert Gereau (WashU Anesthesiology)
Collaborator: David Ornitz (WashU Developmental Biology)
Reversibility of amyloid-induced mitochondrial dysfunction in Alzheimer’s disease
2019 Award
Principal Investigator: Jin-Moo Lee (WashU Neurology)
Collaborator: Song Hu (WashU Biomedical Engineering)
SARM1 inhibition as a novel therapeutic strategy for Cln1 disease
2019 Award
Principal Investigator: Aaron DiAntonio (WashU Developmental Biology)
Collaborator: Jonathan Cooper (WashU Pediatrics), Mark Sands (WashU Medicine)
Internet of things (IoT) monitoring of rodent home-cages to understand circadian plasticity
2019 Award
Principal Investigator: Alexxai Kravitz (WashU Psychiatry)
Collaborator: Erik Herzog (WashU Biology)
DNA methylation in Alzheimer’s disease
2019 Award
Principal Investigator: Oscar Harari (WashU Psychiatry)
Collaborator: Ting Wang (WashU Genetics)
Reprogramming rod photoreceptors to treat retinal degeneration
2018 Award
Principal Investigator: Joseph Corbo (WashU Pathology & Immunology)
Collaborator: Vladimir Kefalov (WashU Ophthalmology & Visual Sciences)
Developing Biomarkers for chemotherapy-induced peripheral neuropathy
2018 Award
Principal Investigator: Stefanie Geisler (WashU Neurology)
Collaborator: Amanda Cashen (WashU Medicine), Anne Fagan (WashU Neurology)
Defining the mechanisms by which MS4A4A regulates TREM2 in Alzheimer disease
2018 Award
Principal Investigator: Celeste Karch (WashU Psychiatry)
Collaborator: Thomas Brett (WashU Medicine), Laura Piccio (WashU Neurology)
Utilizing Human Embryonic Stem Cell-Based Disease Models to Identify the Malignant Epigenetic State in Glioblastoma
2018 Award
Principal Investigator: Albert Kim (WashU Neurosurgery)
Collaborator: Andrew Yoo (WashU Developmental Biology), Jeffrey Millman (WashU Medicine)
Identification of Repurposed Prescription Medications as Neuroprotective Therapy for Amyotrophic Lateral Sclerosis
2018 Award
Principal Investigator: Brad Racette (WashU Neurology)
Collaborator: Timothy Miller (WashU Neurology)
Previous Pilot Awards
Hope Center Pilot awards are two-year projects. Click below to learn details about past pilot projects.
