Active Pilot Projects

Pilot Project awards in 2018 and 2019 Read More

Determining the pathogenic role of FGFR3 autoantibodies in idiopathic small fiber neuropathy

2019 Award

Principal Investigator: Robert Gereau (WashU Anesthesiology)
Collaborator: David Ornitz (WashU Developmental Biology)

Pilot Project Details

Reversibility of amyloid-induced mitochondrial dysfunction in Alzheimer’s disease

2019 Award

Principal Investigator: Jin-Moo Lee (WashU Neurology)
Collaborator: Song Hu (WashU Biomedical Engineering)

Pilot Project Details

SARM1 inhibition as a novel therapeutic strategy for Cln1 disease

2019 Award

Principal Investigator: Aaron DiAntonio (WashU Developmental Biology)
Collaborator: Jonathan Cooper (WashU Pediatrics), Mark Sands (WashU Medicine)

Pilot Project Details

Internet of things (IoT) monitoring of rodent home-cages to understand circadian plasticity

2019 Award

Principal Investigator: Alexxai Kravitz (WashU Psychiatry)
Collaborator: Erik Herzog (WashU Biology)

Pilot Project Details

DNA methylation in Alzheimer’s disease

2019 Award

Principal Investigator: Oscar Harari (WashU Psychiatry)
Collaborator: Ting Wang (WashU Genetics)

Pilot Project Details

Reprogramming rod photoreceptors to treat retinal degeneration

2018 Award

Principal Investigator: Joseph Corbo (WashU Pathology & Immunology)
Collaborator: Vladimir Kefalov (WashU Ophthalmology & Visual Sciences)

Pilot Project Details

Developing Biomarkers for chemotherapy-induced peripheral neuropathy

2018 Award

Principal Investigator: Stefanie Geisler (WashU Neurology)
Collaborator: Amanda Cashen (WashU Medicine), Anne Fagan (WashU Neurology)

Pilot Project Details

Defining the mechanisms by which MS4A4A regulates TREM2 in Alzheimer disease

2018 Award

Principal Investigator: Celeste Karch (WashU Psychiatry)
Collaborator: Thomas Brett (WashU Medicine), Laura Piccio (WashU Neurology)

Pilot Project Details

Utilizing Human Embryonic Stem Cell-Based Disease Models to Identify the Malignant Epigenetic State in Glioblastoma

2018 Award

Principal Investigator: Albert Kim (WashU Neurosurgery)
Collaborator: Andrew Yoo (WashU Developmental Biology), Jeffrey Millman (WashU Medicine)

Pilot Project Details

Identification of Repurposed Prescription Medications as Neuroprotective Therapy for Amyotrophic Lateral Sclerosis

2018 Award

Principal Investigator: Brad Racette (WashU Neurology)
Collaborator: Timothy Miller (WashU Neurology)

Pilot Project Details

Previous Pilot Awards

Hope Center Pilot awards are two-year projects.  Click below to learn details about past pilot projects.

Previous pilot awards