Active Pilot Projects

2013/2014 Pilot Projects Read More

Neuronal subtype-specific vulnerability in tauopathies using reprogramming methods in human somatic and stem cells

2014 Award
Principal Investigator: Celeste Karch (WUSTL Psychiatry)
Co-Investigator: Andrew Yoo (WUSTL Developmental Biology)

Pilot Project Details

Identification and functional characterization of rare variants in DNAJC5/CSP gene associated with Alzheimer Disease

2014 Award
Principal Investigators: Carlos Cruchaga (WUSTL Psychiatry) and Bruno Benitez (WUSTL Internal Medicine)

Pilot Project Details

Characterization of neural bridge circuits for spinal cord repair

2014 Award
Principal Investigator: Shelly Sakiyama-Elbert (WUSTL Biomedical Engineering)
Co-Investigator: Dennis Barbour (WUSTL Biomedical Engineering)

Pilot Project Details

MR Elastography and CSF Biomarkers in Post-Hemorrhagic Hydrocephalus

2014 Award
Principal Investigator: David Limbrick (WUSTL Neurosurgery)
Co-Investigators: Pat McAllister (WUSTL Neurosurgery), Philip Bayly (WUSTL Mechanical Engineering), Robyn Klein (WUSTL Internal Medicine)

Pilot Project Details

Role of nicotinamide adenine dinucleotide (NAD+) metabolism in the pathogenesis of retinal neurodegeneration

2014 Award
Principal Investigator: Shin-Ichiro Imai (WUSTL Developmental Biology)
Co-Investigator: Rajendra Apte (WUSTL Ophthalmology & Visual Sciences)

Pilot Project Details

Promoting axonal regeneration in models of ALS via activation of the preconditioning response in iPSC-derived human neurons

2013 Award
Principal Investigator: Aaron DiAntonio (WUSTL Developmental Biology)
Co-Investigators: Jeffrey Milbrandt (WUSTL Genetics), Timothy Miller (WUSTL Neurology)

Pilot Project Details

TREM2 signaling as a biomarker and therapeutic target in ALS

2013 Award
Principal Investigator: Matthew Harms (WUSTL Neurology)
Co-Investigators: Timothy Miller (WUSTL Neurology), Marco Colonna (WUSTL Pathology & Immunology)

Pilot Project Details

Using biosensors to identify therapy-driven brain reorganization in children

2013 Award
Principal Investigator: Bradley Schlaggar (WUSTL Neurology)
Co-Investigators: Nico Dosenbach (WUSTL Neurology), Catherine Lang (WUSTL Physical Therapy), Steve Petersen (WUSTL Neurology)

Pilot Project Details

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Previous Pilot Awards

Hope Center Pilot awards are two-year projects.  Click below to learn details about past pilot projects.

Previous pilot awards