Neuronal subtype-specific vulnerability in tauopathies using reprogramming methods in human somatic and stem cells
2014 Award
Principal Investigator: Celeste Karch (WUSTL Psychiatry)
Co-Investigator: Andrew Yoo (WUSTL Developmental Biology)
Identification and functional characterization of rare variants in DNAJC5/CSP gene associated with Alzheimer Disease
2014 Award
Principal Investigators: Carlos Cruchaga (WUSTL Psychiatry) and Bruno Benitez (WUSTL Internal Medicine)
Characterization of neural bridge circuits for spinal cord repair
2014 Award
Principal Investigator: Shelly Sakiyama-Elbert (WUSTL Biomedical Engineering)
Co-Investigator: Dennis Barbour (WUSTL Biomedical Engineering)
MR Elastography and CSF Biomarkers in Post-Hemorrhagic Hydrocephalus
2014 Award
Principal Investigator: David Limbrick (WUSTL Neurosurgery)
Co-Investigators: Pat McAllister (WUSTL Neurosurgery), Philip Bayly (WUSTL Mechanical Engineering), Robyn Klein (WUSTL Internal Medicine)
Role of nicotinamide adenine dinucleotide (NAD+) metabolism in the pathogenesis of retinal neurodegeneration
2014 Award
Principal Investigator: Shin-Ichiro Imai (WUSTL Developmental Biology)
Co-Investigator: Rajendra Apte (WUSTL Ophthalmology & Visual Sciences)
Promoting axonal regeneration in models of ALS via activation of the preconditioning response in iPSC-derived human neurons
2013 Award
Principal Investigator: Aaron DiAntonio (WUSTL Developmental Biology)
Co-Investigators: Jeffrey Milbrandt (WUSTL Genetics), Timothy Miller (WUSTL Neurology)
TREM2 signaling as a biomarker and therapeutic target in ALS
2013 Award
Principal Investigator: Matthew Harms (WUSTL Neurology)
Co-Investigators: Timothy Miller (WUSTL Neurology), Marco Colonna (WUSTL Pathology & Immunology)
Using biosensors to identify therapy-driven brain reorganization in children
2013 Award
Principal Investigator: Bradley Schlaggar (WUSTL Neurology)
Co-Investigators: Nico Dosenbach (WUSTL Neurology), Catherine Lang (WUSTL Physical Therapy), Steve Petersen (WUSTL Neurology)
Previous Pilot Awards
Hope Center Pilot awards are two-year projects. Click below to learn details about past pilot projects.
