News & Publications for:

Alison Goate

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer’s disease

Posted on October 23, 2017

Rebecca Sims, Sven J van der Lee, Adam C Naj, Céline Bellenguez, Nandini Badarinarayan, Johanna Jakobsdottir, Brian W Kunkle, et al: 2017 Nature Genetics Volume 49, Issue 9, 1 September 2017, Pages 1373-1384 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: ,

Genome-wide, high-content siRNA screening identifies the Alzheimer’s genetic risk factor FERMT2 as a major modulator of APP metabolism

Posted on September 14, 2017

Julien ChapuisEmail authorAmandine FlaigBenjamin Grenier-BoleyFanny EysertVirginie PottiezGaspard DeloisonAlexandre VandeputteAnne-Marie AyralTiago MendesShruti DesaiAlison M. Goate, et al.: 2017 Acta Neuropathologica, Volume 133, Issue 6, Pages 955-966 Read More

Posted in: Neurogenetics Faculty:

Genome-wide pleiotropy between Parkinson disease and autoimmune diseases

Posted on July 28, 2017

Aree Witoelar, Iris E. Jansen, Yunpeng Wang, Rahul S. Desikan, J. Raphael Gibbs, Cornelis Blauwendraat, et al: 2017 JAMA Neurology Volume 74, Issue 7, Pages 780-792 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: ,

Genetics of β-amyloid precursor protein in alzheimer’s disease

Posted on June 26, 2017

Julia, T.C.W.Email Author, Goate, A.M.: 2017 Cold Spring Harbor Perspectives in Medicine Volume 7, Issue 6, Article number a024539 Read More

Posted in: Neurogenetics, Publications Faculty:

Age and Amyloid Effects on Human Central Nervous System Amyloid-Beta Kinetics

Posted on July 20, 2015

Patterson BW, Elbert DL, Mawuenyega KG, Kasten T, Ovod V, Ma S, Xiong C, Chott R, Yarasheski K, Sigurdson W, Zhang L, Goate A, Benzinger T, Morris JC, Holtzman D, Bateman RJ: 2015 ANNALS of Neurology, 10.1002/ana.24454 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Neurogenetics, Neurogenetics & Transcriptomics, Pilot Projects, Publications Faculty: , , ,