News & Publications for:

Carl Frieden

Functional insights from biophysical study of TREM2 interactions with apoE and Aβ1‐42

Posted on November 4, 2020

Daniel L. Kober, Melissa D. Stuchell‐Brereton, Colin E. Kluender, Hunter B. Dean, Michael R. Strickland, Deborah F. Steinberg, Samantha S. Nelson, Berevan Baban, David M. Holtzman, Carl Frieden, Jennifer Alexander‐Brett, Erik D. Roberson, Yuhua Song, Tom J. Brett. Alzheimers Dementia. 2020 Oct 8 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: , ,

19F NMR reveals the conformational properties of free thrombin and its zymogen precursor prethrombin-2

Posted on June 24, 2020

Eliza A. Ruben, Prafull S. Gandhi, Zhiwei Chen, Sarah K. Koester, Gregory T. DeKoster, Carl Frieden and Enrico Di Cera. The Journal of Biological Chemistry, Volume 295, Issue 24, 12 June 2020, Pages 8227-8235 Read More

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Charge Reduction of Membrane Proteins in Native Mass Spectrometry Using Alkali Metal Acetate Salts

Posted on May 27, 2020

John T. Petroff II, Ailing Tong, Lawrence J. Chen, Gregory T. Dekoster, Farha Khan, Jeff Abramson, Carl Frieden, and Wayland W. L. Cheng. Analytical Chemistry, Volume 92, Issue 9, 5 May 2020, Pages 6622-6630 Read More

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Native Mass Spectrometry, Ion Mobility, Electron-Capture Dissociation, and Modeling Provide Structural Information for Gas-Phase Apolipoprotein E Oligomers

Posted on May 30, 2019

Hanliu Wang, Joseph Eschweiler, Weidong Cui, Hao Zhang, Carl Frieden, Brandon T. Ruotolo, Michael L. Gross. Journal of the American Society for Mass Spectrometry, Volume 30, Issue 5, 1 May 2019, Pages 876-885 Read More

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Protein oligomerization as a metabolic control mechanism: Application to apoE

Posted on March 6, 2019

Carl Frieden. Protein Science 2019 Read More

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