News & Publications for:

Carl Frieden

Structure-function analysis of the curli accessory protein CsgE defines surfaces essential for coordinating amyloid fiber formation

Posted on November 7, 2018

Roger D. Klein, Qin Shu, Zachary T. Cusumano, Kanna Nagamatsu, Nathaniel C. Gualberto, Aaron J. L. Lynch, Chao Wu, Wenjie Wang, Neha Jain, Jerome S. Pinkner, Gaya K. Amarasinghe, Scott J. Hultgren, Carl Frieden, Matthew R. Chapman. mBio, Volume 9, Issue 4, July-August 2018, Article number e01349-18 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Peptide-Level Interactions between Proteins and Small-Molecule Drug Candidates by Two Hydrogen-Deuterium Exchange MS-Based Methods: The Example of Apolipoprotein E3

Posted on October 31, 2017

Hanliu Wang, Don L. Rempel, Daryl Giblin, Carl Frieden, and Michael L. Gross: 2017 Analytical Chemistry, Volume 89, Issue 20, 17 October, Pages 10687-10695 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Deamidation Slows Curli Amyloid-Protein Aggregation

Posted on July 10, 2017

Hanliu Wang, Qin Shu, Carl Frieden, and Michael L. Gross: 2017 Biochemistry Volume 56, Issue 23, 13, Pages 2865-2872 Read More

Posted in: HPAN, Neurodegeneration Faculty:

ApoE: In Vitro Studies of a Small Molecule Effector

Posted on June 5, 2016

Mondal T, Wang H, Dekoster GT, et al: 2016 Biochemistry, 55(18), pp 2613-2621 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Continuous and Pulsed Hydrogen-Deuterium Exchange and Mass Spectrometry Characterize CsgE Oligomerization

Posted on November 16, 2015

Wang, H. et al.; 2015. Biochemistry, 54(42), pp 6475-6481 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: