News & Publications for:

Carl Frieden

Unmasking the roles of N- and C-terminal flanking sequences from exon 1 of huntingtin as modulators of polyglutamine aggregation

Posted on February 11, 2014

Crick, S. L., Ruff, K. M, Garai, K., Frieden, C. and Pappu, R. V.; Proc Nat’l Acad Sci (USA) 110 20075-20080 (2013) Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: ,

Concerning the structure of apoE

Posted on February 11, 2014

C. Frieden and K. Garai; Prot. Sci 22 1820-1825 (2013) Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

ApoE influences amyloid-β (Aβ) clearance despite minimal apoE/Aβ association in physiological conditions

Posted on February 11, 2014

P. B. Verghese, J. M. Castellano, K. Garai, Y. Wang, H. Jiang, A. Shah, G. Bu, C. Frieden, and D. M. Holtzman; Proc Natl Acad Sci (USA) 110 E1807-1816 (2013) Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: ,

Quantitative analysis of the time course of Aβ oligomerization and subsequent growth steps using tetramethylrhodamine-labeled Aβ

Posted on February 11, 2014

K. Garai and C. Frieden; Proc Natl Acad Sci (USA) 110 3321-3326 (2013) Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Structural differences between apoE3 and apoE4 may be useful in developing therapeutic agents for Alzheimer’s disease

Posted on February 11, 2014

C. Frieden and K Garai; Proc Natl Acad Sci (USA) 109 8913-8918 (2012). Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: