News & Publications for:

Carlos Cruchaga

CSF progranulin increases in the course of Alzheimer’s disease and is associated with sTREM2, neurodegeneration and cognitive decline

Posted on December 6, 2018

Marc Suárez‐Calvet, Anja Capell, Miguel Ángel Araque Caballero, Estrella Morenas‐Rodríguez, Katrin Fellerer, Nicolai Franzmeier, Gernot Kleinberger, Erden Eren, Yuetiva Deming, Laura Piccio, Celeste M Karch, Carlos Cruchaga, Katrina Paumier, Randall J Bateman, Anne M Fagan, John C Morris, Johannes Levin, Adrian Danek, Mathias Jucker, Colin L Masters, Martin N Rossor, John M Ringman, Leslie M Shaw, John Q Trojanowski, Michael Weiner, Michael Ewers, Christian Haass, the Dominantly Inherited Alzheimer Network, the Alzheimer’s Disease Neuroimaging Initiative. EMBO Molecular Medicine, 2018, Article number e9712 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , ,

Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging

Posted on November 12, 2018

Qi Yan, Kwangsik Nho, Jorge L. Del-Aguila, Xingbin Wang, Shannon L. Risacher, Kang-Hsien Fan, Beth E. Snitz, Howard J. Aizenstein, Chester A. Mathis, Oscar L. Lopez, F. Yesim Demirci, Eleanor Feingold, William E. Klunk, Andrew J. Saykin, for the Alzheimer’s Disease Neuroimaging Initiative (ADNI), Carlos Cruchaga & M. Ilyas Kamboh . Molecular Psychiatry 2018 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty:

Utility of perfusion PET measures to assess neuronal injury in Alzheimer’s disease

Posted on November 12, 2018

Nelly Joseph-Mathurin, Yi Su, Tyler M. Blazey, Mateusz Jasielec, Andrei Vlassenko, Karl Friedrichsen, Brian A. Gordon, Russ C. Hornbeck, Lisa Cash, Beau M. Ances, Thomas Veale, David M. Cash, Adam M. Brickman, Virginia Buckles, Nigel J. Cairns, Carlos Cruchaga, Alison Goate, Clifford R. Jack, Celeste Karch, William Klunk, Robert A. Koeppe, Daniel S. Marcus, Richard Mayeux, Eric McDade, James M. Noble, John Ringman, Andrew J. Saykin, Paul M. Thompson, Chengjie Xiong, John C. Morris, Randall J. Bateman and Tammie L.S. Benzinger. Alzheimer’s and Dementia: Diagnosis, Assessment and Disease Monitoring, Volume 10, 1 January 2018, Pages 669-677 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , , ,

Effect of BDNFVal66Met on disease markers in dominantly inherited Alzheimer’s disease

Posted on September 13, 2018

Yen Ying Lim Ph.D. Jason Hassenstab Ph.D. Alison Goate Ph.D. Anne M. Fagan Ph.D. Tammie L.S. Benzinger M.D., Ph.D. Carlos Cruchaga Ph.D. Eric McDade D.O. Jasmeer Chhatwal M.D., Ph.D. Johannes Levin M.D. Martin R. Farlow M.D. Neill R. Graff‐Radford M.D. Christoph Laske M.D. Colin L. Masters M.D. Stephen Salloway M.D. Peter Schofield Ph.D. John C. Morris M.D. Paul Maruff Ph.D. Randall J. Bateman M.D. on behalf of the Dominantly Inherited Alzheimer Network. Annals of Neurology, 2018 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , ,

Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network

Posted on August 9, 2018

Celeste M. Karch, Damián Hernández, Jen-Chyong Wang, Jacob Marsh, Alex W. Hewitt, Simon Hsu, Joanne Norton, Denise Levitch, Tamara Donahue, Wendy Sigurdson, Bernardino Ghetti, Martin Farlow, Jasmeer Chhatwal, Sarah Berman, Carlos Cruchaga, John C. Morris, Randall J. Bateman, the Dominantly Inherited Alzheimer Network (DIAN), Alice Pébay and Alison M. Goate. Alzheimer’s Research and Therapy, Volume 10, Issue 1, 25 July 2018, Article number 69 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , ,