News & Publications for:

Carlos Cruchaga

Genes linked to Alzheimer’s risk, resilience ID’d

Posted on August 21, 2019

Genes in the brain’s immune cells may point to strategy to protect against the disease Read More

Posted in: Axon Injury & Repair, HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, News Faculty: , ,

The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer’s disease risk

Posted on August 21, 2019

Yuetiva Deming, Fabia Filipello, Francesca Cignarella, Claudia Cantoni, Simon Hsu, Robert Mikesell, Zeran Li, Jorge L Del-Aguila, Umber Dube, Fabiana Geraldo Farias, Joseph Bradley, John Budde, Laura Ibanez, Maria Victoria Fernandez, Kaj Blennow, Henrik Zetterberg, Amanda Heslegrave, Per M Johansson, Johan Svensson, Bengt Nellgård, Alberto Lleo, Daniel Alcolea, Jordi Clarimon, Lorena Rami, José Luis Molinuevo, Marc Suárez-Calvet, Estrella Morenas-Rodríguez, Gernot Kleinberger, Michael Ewers, Oscar Harari, Christian Haass, Thomas J Brett, Bruno A. Benitez, Celeste M. Karch, Laura Piccio and Carlos Cruchaga. Science Translational Medicine, Vol 11, Issue 505,14 August 2019 Read More

Posted in: Axon Injury & Repair, HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , ,

Higher Body Mass Index Is Associated with Lower Cortical Amyloid-β Burden in Cognitively Normal Individuals in Late-Life

Posted on June 27, 2019

Thirunavu, Vineeth; McCullough, Austin; Su, Yi; Flores, Shane; Dincer, Aylin; Morris, John C.; Cruchaga, Carlos; Benzinger, Tammie L.S.; Gordon, Brian. Journal of Alzheimer’s Disease, Volume 69, Issue 3, 2019, Pages 817-827 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , ,

TREM2 brain transcript-specific studies in AD and TREM2 mutation carriers

Posted on May 24, 2019

Jorge L. Del-Aguila, Bruno A. Benitez, Zeran Li, Umber Dube, Kathie A. Mihindukulasuriya, John P. Budde, Fabiana H. G. Farias, Maria Victoria Fernández, Laura Ibanez, Shan Jiang, Richard J. Perrin, Nigel J. Cairns, John C. Morris, Oscar Harari and Carlos Cruchaga. Molecular Neurodegeneration, Volume 14, Issue 1, 8 May 2019, Article number 18 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , ,

Quantification of white matter cellularity and damage in preclinical and early symptomatic Alzheimer’s disease

Posted on April 1, 2019

Qing Wang, Yong Wang, Jingxia Liu, Courtney L. Sutphen, Carlos Cruchaga, Tyler Blazey, Brian A. Gordon, Yi Su, Charlie Chen, Joshua S. Shimony, Beau M. Ances, Nigel J. Cairns, Anne M. Fagan, John C. Morris, Tammie L.S. Benzinger. NeuroImage: Clinical, Volume 22, 1 January 2019, Article number 101767 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , ,