News & Publications for:

Daniel Ory

A murine Niemann-Pick C1 (NPC1) I1061T knockin model recapitulates the pathological features of the most prevalent human disease allele

Posted on October 20, 2016

Praggastis M, Tortelli B, Zhang J, Fujiwara H, Sidhu R, Chacko A, Chen Z, Lieberman AP, Davidson C, Walkley SU, Pipalia NH, Maxfield FR, Schaffer JE, and Ory DS: 2015 J Neuroscience, 35:8091-8106. PMCID: PMC4444535 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Publications Faculty:

Development of a bile acid-based newborn screen for Niemann-Pick disease type C

Posted on June 5, 2016

Jiang X, Sidhu R, Mydock-McGrane L, et al: 2016 Science Translational Medicine, 8(337) Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Publications Faculty:

Intracisternal cyclodextrin prevents cerebellar dysfunction and Purkinje cell death in feline Niemann-Pick type C1 disease

Posted on April 9, 2015

Vite CH, Bagel JH, Swain GP, et al: 2015 Science Translational Medicine, 7(276), art number 276ra26 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Publications Faculty:

Plasma sphingolipids associated with chronic obstructive pulmonary disease phenotypes

Posted on March 12, 2015

Bowler RP, Jacobson S, Cruickshank C, et al: 2015 American Journal of Respiratory and Critical Care Medicine, 191(3), pp275-284 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Publications Faculty: