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David Holtzman

David Holtzman‘s Faculty Page

Dural lymphatics regulate clearance of extracellular tau from the CNS

Posted on March 13, 2019

Tirth K. Patel, LeMoyne Habimana-Griffin, Xuefeng Gao, Baogang Xu, Samuel Achilefu, Kari Alitalo, Celia A. McKee, Patrick W. Sheehan, Erik S. Musiek, Chengjie Xiong, Dean Coble and David M. Holtzman. Molecular Neurodegeneration, Volume 14, Issue 1, 27 February 2019, Article number 11 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: ,

Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer’s disease

Posted on March 13, 2019

Suzanne E. Schindler, Yan Li, Kaitlin W. Todd, Elizabeth M. Herries, Rachel L. Henson, Julia D. Gray, Guoqiao Wang, Danielle L. Graham, Leslie M. Shaw, John Q. Trojanowski, Jason J. Hassenstab, Tammie L.S. Benzinger, Carlos Cruchaga, Mathias Jucker, Johannes Levin, Jasmeer P. Chhatwal, James M. Noble, John M. Ringman, Neill R. Graff-Radford, David M. Holtzman, Jack H. Ladenson, John C. Morris, Randall J. Bateman, Chengjie Xiong, Anne M. Fagan for the Dominantly Inherited Alzheimer Network. Alzheimer’s and Dementia 2019 Read More

Posted in: Clocks & Sleep, HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , ,

Predicting Short-term MCI-to-AD Progression Using Imaging, CSF, Genetic Factors, Cognitive Resilience, and Demographics

Posted on March 5, 2019

Yogatheesan Varatharajah, Vijay K. Ramanan, Ravishankar Iyer, Prashanthi Vemuri & For the Alzheimer’s Disease Neuroimaging Initiative. Scientific Reports, Volume 9, Issue 1, 1 December 2019, Article number 2235 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: , , , ,

The sleep-wake cycle regulates brain interstitial fluid tau in mice and csf tau in humans

Posted on February 28, 2019

Jerrah K. Holth, Sarah K. Fritschi, Chanung Wang, Nigel P. Pedersen, John R. Cirrito, Thomas E. Mahan, Mary Beth Finn, Melissa Manis, Joel C. Geerling, Patrick M. Fuller, Brendan P. Lucey, David M. Holtzman. Science 2019 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: , ,

Multi-Modal Home Sleep Monitoring in Older Adults

Posted on February 21, 2019

Cristina D. Toedebusch, Jennifer S. McLeland, Claire M. Schaibley, Ian R. Banks, Jill Boyd, John C. Morris, David M. Holtzman, Brendan P. Lucey. Journal of visualized experiments : JoVE, Issue 143, 26 January 2019 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: , ,