News & Publications for:

Fumihiko Urano

Transcriptional regulation of X-Box-binding protein One (XBP1) by hepatocyte nuclear factor 4- (HNF4-) Is vital to beta-cell function

Posted on May 31, 2016

Moore BD, Jin RU, Lo H, et al: 2016 Journal of Biological Chemistry, 291(12), pp 6146-6157 Read More

Posted in: HPAN, Neurodegeneration, NeuroRestorative Therapy, Publications Faculty:

A calcium-dependent protease as a potential therapeutic target for Wolfram syndrome

Posted on December 18, 2014

Simin Lu, Kohsuke Kanekura, Takashi Hara, Jana Mahadevan, Larry D. Spears, Christine M. Oslowski, Rita Martinez, Mayu Yamazaki-Inoue, Masashi Toyoda, Amber Neilson, Patrick Blanner, Cris M. Brown, Clay F. Semenkovich, Bess A. Marshall, Tamara Hershey, Akihiro Umezawa, Peter A. Greer, and Fumihiko Urano; 2014 Proceedings of the National Academy of Sciences of the United States of America, 11(49), p E5292-E5301 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, Publications Faculty: ,

Calcium efflux from the endoplasmic reticulum leads to β-cell death

Posted on April 10, 2014

Takashi Hara, Jana Mahadevan, Kohsuke Kanekura, Mariko Hara, Simin Lu, Fumikiho Urano; 2014 Endocrinology 155(3) pp. 758-768 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

WFS1 Is a Novel Component of the Unfolded Protein Response and Maintains Homeostasis of the Endoplasmic Reticulum in Pancreatic β-Cells

Posted on February 11, 2014

Fonseca, S.G., Fukuma, M., Lipson, K., Nguyen, L.X., Allen, J.R., Oka, Y., and Urano F.; J Biol Chem, 280(47): 39609-615, 2005. Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: