News & Publications for:

Gilbert Gallardo

Gallardo received 5-year, $1.96M grant from National Institute on Aging/NIH

Posted on February 6, 2020

From the WashU Newsroom… Gilbert Gallardo, assistant professor of neurology at the School of Medicine, received a five-year, $1.96 million grant from the National Institute On Aging of the National Institutes of Health (NIH) for research titled “Engineering anti-tau intrabodies that reduce tauopathy by either the proteasome, lysosome, or chaperone mediated autophagy.” Read More

Posted in: HPAN, Neurodegeneration, News Faculty:

Targeting tauopathy with engineered tau-degrading intrabodies

Posted on October 30, 2019

Gilbert Gallardo, Connie H. Wong, Sara M. Ricardez, Carolyn N. Mann, Kent H. Lin, Cheryl E. G. Leyns, Hong Jiang & David M. Holtzman. Molecular neurodegeneration, Volume 14, Issue 1, 22 October 2019, Page 38 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: ,

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

Posted on September 27, 2017

Yang Shi, Kaoru Yamada[…], Gilbert Gallardo, John Morris, Carlos Cruchaga, Anne Fagan […] David M. Holtzman. Nature. 2017 Sep 28;549(7673):523-527. doi: 10.1038/nature24016. Epub 2017 Sep 20. Read More

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AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy

Posted on May 27, 2017

Christina Ising, Gilbert Gallardo, Cheryl E.G. Leyns, Connie H. Wong, Hong Jiang, Floy Stewart, Lauren J. Koscal, Joseph Roh, Grace O. Robinson, Javier Remolina Serrano, David M. Holtzman. J Exp Med. 2017 May 1;214(5):1227-1238. doi: 10.1084/jem.20162125. Epub 2017 Apr 17. Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: ,

An α2-Na/K ATPase/α-adducin complex in astrocytes triggers non–cell autonomous neurodegeneration

Posted on December 27, 2014

Gilbert Gallardo, Jessica Barowski, John Ravits, Teepu Siddique, Jerry B Lingrel, Janice Robertson, Hanno Steen & Azad Bonni. Nat Neurosci. 2014 Dec;17(12):1710-9. doi: 10.1038/nn.3853. Epub 2014 Oct 26. Read More

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