News & Publications for:

Meredith Jackrel

Hsp104 and Potentiated Variants Can Operate as Distinct Nonprocessive Translocases

Posted on April 30, 2019

Clarissa L. Durie, Jia Bei Lin, Nathaniel W. Scull, Korrie L. Mack, Meredith E. Jackrel, Elizabeth A. Sweeny, Laura M. Castellano, James Shorter, Aaron L. Lucius. Biophysical Journal 2019 Read More

Posted in: HPAN, Neurodegeneration Faculty:

Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events

Posted on March 12, 2019

Karolina Michalska, Kaiming Zhang, Zachary M. March, Catherine Hatzos-Skintges, Grigore Pintilie, Lance Bigelow, Laura M. Castellano, Leann J. Miles, Meredith E. Jackrel, Edward Chuang, Robert Jedrzejczak, James Shorter, Wah Chiu, Andrzej Joachimiak. Structure, Volume 27, Issue 3, 5 March 2019, Pages 449-463.e7 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Engineering the right protein

Posted on February 28, 2019

Chemists in Arts & Sciences are working to engineer proteins that may help counter devastating neurodegenerative diseases such as Alzheimer’s, Parkinson’s, and ALS. Read More

Posted in: HPAN, Neurodegeneration, News Faculty:

Potentiating Hsp104 activity via phosphomimetic mutations in the middle domain

Posted on August 7, 2018

Amber Tariq, JiaBei Lin, Megan M Noll, Mariana P Torrente, Korrie L Mack,Oscar Hernandez Murillo, Meredith E Jackrel, James Shorter. FEMS Yeast Research, Volume 18, Issue 5, 1 August 2018, Article number foy042 Read More

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