News & Publications for:

Mingjie Li

Protein that rouses the brain from sleep may be target for Alzheimer’s prevention

Posted on December 4, 2014

From the WUSTL Newsroom… A protein that stimulates the brain to awaken from sleep may be a target for preventing Alzheimer’s disease, a study by researchers at Washington University School of Medicine in St. Louis suggests. In recent years, scientists at Washington University have established links between sleep problems and Alzheimer’s. For example, they have shown in people and in mice that sleep loss contributes to the growth of brain plaques characteristic of Alzheimer’s, and increases … Read More Read More

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Heparan sulfate proteoglycans mediate internalization and propagation of specific proteopathic seeds

Posted on September 3, 2013

Holmes BB, DeVos SL, Kfoury N, Li M, Jacks R, Yanamandra K, Ouidja MO, Brodsky FM, Marasa J, Bagchi DP, Kotzbauer PT, Miller TM, Papy-Garcia D, Diamond MI; (2013) Proceedings of the National Academy of Sciences of the United States of America, 110 (33), pp. E3138-E3147. Read More

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Optimal promoter usage for lentiviral vector-mediated transduction of cultured central nervous system cells

Posted on October 13, 2010

Li M, Husic N, Lin Y, Christensen H, Malik I, McIver S, Daniels CM, Harris DA, Kotzbauer PT, Goldberg MP, Snider BJ (2010). J Neurosci Methods, 189(1):56-64. PMID:20347873 Read More

Posted in: HPAN, Neurodegeneration, Pilot Projects, Publications, Therapeutics & Diagnostics, Viral Vectors Faculty: , ,

Lentiviral vector delivery of siRNA and shRNA encoding genes into cultured and primary hematopoietic cells

Posted on October 13, 2008

Li M, Rossi JJ (2008). Methods Mol Biol, 433:287-299. PMID:18679631 Read More

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Safety and efficacy of a lentiviral vector containing three anti-HIV genes–CCR5 ribozyme, tat-rev siRNA, and TAR decoy–in SCID-hu mouse-derived T cells

Posted on October 13, 2007

Anderson J, Li MJ, Palmer B, Remling L, Li S, Yam P, Yee JK, Rossi J, Zaia J, Akkina R (2007). Mol Ther, 15:1182-1188. PMID:17406343 Read More

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