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Nigel Cairns

Nigel Cairns‘s Faculty Page

TREM2 Maintains Microglial Metabolic Fitness in Alzheimer’s Disease

Posted on August 11, 2017

Tyler K. Ulland, Wilbur M. Song, Stanley Ching-Cheng Huang, Jason D. Ulrich, Alexey Sergushichev, Wandy L. Beatty, Alexander A. Loboda, Yingyue Zhou, Nigel J. Cairns, Amal Kambal, Ekaterina Loginicheva, Susan Gilfillan, Marina Cella, Herbert W. Virgin, Emil R. Unanue, Yaming Wang, Maxim N. Artyomov, David M. Holtzman, Marco Colonna: 2017 Cell Volume 170, Issue 4, p649–663.e13 Read More

Posted in: Axon Injury & Repair, Clocks & Sleep, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , ,

Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease

Posted on June 1, 2017

Niklas Mattsson, MD, PhD, Ulf Andreasson, PhD, Henrik Zetterberg, MD, PhD, et al: 2017 JAMA Neurol.;74(5):557-566. Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: , , , ,

TDP-43 expression influences amyloidβ plaque deposition and tau aggregation

Posted on May 5, 2017

Stephani A. Davisa, Kok Ann Gana, James A. Dowellb, Nigel J. Cairnsc, Michael A. Gitchoa: 2017 Neurobiology of Disease, 103 pp 154-162. Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Anti-tau antibody administration increases plasma tau in transgenic mice and patients with tauopathy

Posted on April 20, 2017

K Yanamandra, TK Patel, H Jiang, S Schindler, JD Ulrich, and others: 2017 Science Translational Medicine, 9 (386) eaal2029 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: ,

Human Central Nervous System (CNS) apoE isoforms are increased by age, differentially altered by amyloidosis, and relative amounts reversed in the CNS compared with plasma

Posted on January 20, 2017

Baker-Nigh AT, Mawuenyega KG, Bollinger JG, et al: 2016 Journal of Biological Chemistry, 291(53), pp 27204-27218. Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , ,