News & Publications for:

Oscar Harari

Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP

Posted on December 27, 2018

Shan Jiang, Natalie Wen, Zeran Li, Umber Dube, Jorge Del Aguila, John Budde, Rita Martinez, Simon Hsu, Maria V. Fernandez, Nigel J. Cairns, Dominantly Inherited Alzheimer Network (DIAN), International FTD-Genomics Consortium (IFGC), Oscar Harari, Carlos Cruchaga & Celeste M. Karch . Translational Psychiatry, Volume 8, Issue 1, 1 December 2018, Article number 265 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Pilot Projects, Publications Faculty: , ,

Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure

Posted on June 21, 2018

Zeran Li, Jorge L. Del-Aguila, Umber Dube, John Budde, Rita Martinez, Kathleen Black, Qingli Xiao, Nigel J. Cairns, The Dominantly Inherited Alzheimer Network (DIAN), Joseph D. Dougherty, Jin-Moo Lee, John C. Morris, Randall J. Bateman, Celeste M. Karch, Carlos Cruchaga, Oscar Harari. Genome Medicine, Volume 10, Issue 1, 8 June 2018, Article number 43 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Neurovascular Injury & Repair, Publications Faculty: , , , , , , ,

Evaluation of gene-based family-based methods to detect novel genes associated with familial late onset Alzheimer disease

Posted on April 18, 2018

Maria V. Fernández, John Budde, Jorge L. Del-Aguila, Laura Ibañez, Yuetiva Deming, Oscar Harari, Joanne Norton, John C. Morris, Alison M. Goate, NIA-LOAD family study group, NCRAD and Carlos Cruchaga. Frontiers in Neuroscience, Volume 12, Issue APR, 4 April 2018, Article number 209 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , ,

Assessment of the Genetic Architecture of Alzheimer’s Disease Risk in Rate of Memory Decline

Posted on March 22, 2018

Del-Aguila, Jorge L., […] Carlos Cruchaga. Journal of Alzheimer’s Disease, Volume 62, Issue 2, 2018, Pages 745-756 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , ,

Analysis of neurodegenerative Mendelian genes in clinically diagnosed Alzheimer Disease

Posted on December 21, 2017

Maria Victoria Fernández, Jong Hun Kim, John P. Budde, Kathleen Black, Alexandra Medvedeva, Ben Saef, Yuetiva Deming, Jorge Del-Aguila, Laura Ibañez, Umber Dube, Oscar Harari, Joanne Norton, Rachel Chasse, [ … ], Carlos Cruchaga: PLoS Genetics, Volume 13, Issue 11, November 2017, Article number e1007045 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , ,