News & Publications for:

Oscar Harari

Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease

Posted on November 23, 2020

Laura Ibanez, Jorge A. Bahena, Chengran Yang, Umber Dube, Fabiana H. G. Farias, John P. Budde, Kristy Bergmann, Carol Brenner-Webster, John C. Morris, Richard J. Perrin, Nigel J. Cairns, John O’Donnell, Ignacio Álvarez, Monica Diez-Fairen, Miquel Aguilar, Rebecca Miller, Albert A. Davis, Pau Pastor, Paul Kotzbauer, Meghan C. Campbell, Joel S. Perlmutter, Herve Rhinn, Oscar Harari, Carlos Cruchaga & Bruno A. Benitez. Acta Neuropathologica Communications volume 8, Article number: 196 (2020) Read More

Posted in: Axon Injury & Repair, Clocks & Sleep, HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , , , , ,

Examination of the Effect of Rare Variants in TREM2, ABI3, and PLCG2 in LOAD through Multiple Phenotypes

Posted on November 3, 2020

Claudia Olive, Laura Ibanez, Fabiana H Geraldo Farias, Fengxian Wang, John P Budde, Joanne B Norton, Jen Gentsch, John C Morris, Zeran Li, Umber Dube, Jorge Del-Aguila, Kristy Bergmann, Joseph Bradley, Bruno A Benitez, Oscar Harari, Anne Fagan, Beau Ances, Carlos Cruchaga, Maria Victoria Fernandez. Journal of Alzheimer’s Disease, Volume 77, Issue 4, 2020, Pages 1469-1482 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , ,

TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis

Posted on August 14, 2020

Francesca Cignarella, Fabia Filipello, Bryan Bollman, Claudia Cantoni, Alberto Locca, Robert Mikesell, Melissa Manis, Adiljan Ibrahim, Li Deng, Bruno A. Benitez, Carlos Cruchaga, Danilo Licastro, Kathie Mihindukulasuriya, Oscar Harari, Michael Buckland, David M. Holtzman, Arnon Rosenthal, Tina Schwabe, Ilaria Tassi & Laura Piccio. Acta Neuropathologica 2020 Read More

Posted in: Clocks & Sleep, Lysosome, Neurogenetics & Transcriptomics, Publications Faculty: , , , ,

Overlapping genetic architecture between Parkinson disease and melanoma

Posted on March 27, 2020

Umber Dube, Laura Ibanez, John P. Budde, Bruno A. Benitez, Albert A. Davis, Oscar Harari, Mark M. Iles, Matthew H. Law, Kevin M. Brown, 23andMe Research Team, Melanoma-Meta-analysis Consortium, Carlos Cruchaga. Acta Neuropathologica 2019 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , ,