News & Publications for:

Richard Perrin

Sequence of Alzheimer disease biomarker changes in cognitively normal adults: A cross-sectional study

Posted on December 27, 2020

Jingqin Luo, Folasade Agboola, Elizabeth Grant, Colin L. Masters, Marilyn S. Albert, Sterling C. Johnson, Eric M. McDade, Jonathan Vöglein, Anne M. Fagan, Tammie Benzinger, Parinaz Massoumzadeh, Jason Hassenstab, Randall J. Bateman, John C. Morris, Richard J. Perrin, Jasmeer Chhatwal, Mathias Jucker, Bernardino Ghetti, Carlos Cruchaga, Neill R. Graff-Radford, Peter R. Schofield, Hiroshi Mori, Chengjie Xiong. Neurology, Volume 95, Issue 23, 8 December 2020, Pages e3104-e3116 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , ,

Functional genomic analyses uncover APOE-mediated regulation of brain and cerebrospinal fluid beta-amyloid levels in Parkinson disease

Posted on November 23, 2020

Laura Ibanez, Jorge A. Bahena, Chengran Yang, Umber Dube, Fabiana H. G. Farias, John P. Budde, Kristy Bergmann, Carol Brenner-Webster, John C. Morris, Richard J. Perrin, Nigel J. Cairns, John O’Donnell, Ignacio Álvarez, Monica Diez-Fairen, Miquel Aguilar, Rebecca Miller, Albert A. Davis, Pau Pastor, Paul Kotzbauer, Meghan C. Campbell, Joel S. Perlmutter, Herve Rhinn, Oscar Harari, Carlos Cruchaga & Bruno A. Benitez. Acta Neuropathologica Communications volume 8, Article number: 196 (2020) Read More

Posted in: Axon Injury & Repair, Clocks & Sleep, HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , , , ,

Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN)

Posted on March 18, 2020

Andrew J. Aschenbrenner, Bryan D. James, Eric McDade, Guoqiao Wang, Yen Ying Lim, Tammie L.S. Benzinger, Carlos Cruchaga, Alison Goate, Chengjie Xiong, Richard Perrin, Virginia Buckles, Ricardo Allegri, Sarah B. Berman, Jasmeer P. Chhatwal, Anne Fagan, Martin Farlow, Antoinette O’Connor, Bernardino Ghetti, Neill Graff‐Radford, Jill Goldman Susanne Gräber, Celeste M. Karch, Jae‐Hong Lee, Johannes Levin, Ralph N. Martins, Colin Masters, Hiroshi Mori, James Noble, Stephen Salloway, Peter Schofield, John C. Morris, Randall J. Bateman, Jason Hassenstab, Dominantly Inherited Alzheimer Network. Alzheimer’s and Dementia, Volume 16, Issue 1, 1 January 2020, Pages 219-228 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , ,

A single-nuclei RNA sequencing study of Mendelian and sporadic AD in the human brain

Posted on August 23, 2019

Jorge L. Del-Aguila, Zeran Li, Umber Dube, Kathie A. Mihindukulasuriya, John P. Budde, Maria Victoria Fernandez, Laura Ibanez, Joseph Bradley, Fengxian Wang, Kristy Bergmann, Richard Davenport, John C. Morris, David M. Holtzman, Richard J. Perrin, Bruno A. Benitez, Joseph Dougherty, Carlos Cruchaga & Oscar Harari. Alzheimer’s Research and Therapy, Volume 11, Issue 1, 9 August 2019, Article number 71 Read More

Posted in: Clocks & Sleep, HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , ,

Neuroinflammation and myelin status in Alzheimer’s disease, Parkinson’s disease, and normal aging brains: A small sample study

Posted on July 26, 2019

Fei Han, Richard J. Perrin, Qing Wang, Yong Wang, Joel S. Perlmutter, John C. Morris, Tammie L. S. Benzinger, and Jinbin Xu. Parkinson’s Disease, Volume 2019, 2019, Article number 7975407 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Publications Faculty: , , ,