News & Publications for:

Rohit Pappu

Uncovering molecular grammar

Posted on July 9, 2018

Collaborative team deciphers the protein sequence-encoded mechanism that drives phase separation Read More

Posted in: HPAN, Neurodegeneration, News Faculty:

Differential solvation of intrinsically disordered linkers drives the formation of spatially organized droplets in ternary systems of linear multivalent proteins

Posted on May 23, 2018

Tyler S Harmon, Alex S Holehouse and Rohit V Pappu. New Journal of Physics, Volume 20, Issue 4, April 2018, Article number 045002 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers

Posted on March 28, 2018

Ammon E. Posey, Kiersten M. Ruff, Tyler S. Harmon, Scott L. Crick, Aimin Li, Marc I. Diamond and Rohit V. Pappu. Journal of Biological Chemistry, Volume 293, Issue 10, 2018, Pages 3734-3746 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: ,

Phase separation of a yeast prion protein promotes cellular fitness

Posted on January 17, 2018

Titus M. Franzmann, […], Rohit V. Pappu, Anthony A. Hyman, Simon Alberti. Science, Volume 359, Issue 6371, 5 January 2018, Article number aao5654 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Quantitative analysis of multilayer organization of proteins and RNA in nuclear speckles at super resolution

Posted on December 27, 2017

Jingyi Fei, Mahdieh Jadaliha, Tyler S. Harmon, Isaac T. S. Li, Boyang Hua, Qinyu Hao, Alex S. Holehouse, Matthew Reyer, Qinyu Sun, Susan M. Freier, Rohit V. Pappu, Kannanganattu V. Prasanth, Taekjip Ha: Journal of Cell Science, Volume 130, Issue 24, 1 December 2017, Pages 4180-4192 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: