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Publications

Non-coding variability at the APOE locus contributes to the Alzheimer’s risk

Posted on August 28, 2019

Xiaopu Zhou, Yu Chen, Kin Y. Mok, Timothy C. Y. Kwok, Vincent C. T. Mok, Qihao Guo, Fanny C. Ip, Yuewen Chen, Nandita Mullapudi, Alzheimer’s Disease Neuroimaging Initiative, Paola Giusti-Rodríguez, Patrick F. Sullivan, John Hardy, Amy K. Y. Fu, Yun Li & Nancy Y. Ip. Nature Communications, Volume 10, Issue 1, 1 December 2019, Article number 3310 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Amyloid imaging of dutch-type hereditary cerebral amyloid angiopathy carriers

Posted on August 28, 2019

Aaron P. Schultz, Reina W. Kloet, Hamid R. Sohrabi, Louise van der Weerd, Sanneke van Rooden, Marieke J. H. Wermer ,Laure Grand Moursel, Maqsood Yaqub, Bart N. M. van Berckel, Pratishtha Chatterjee, Samantha L. Gardener, Kevin Taddei, Anne M. Fagan, Tammie L. Benzinger, John C. Morris, Reisa Sperling, Keith Johnson, Randall J. Bateman, Dominantly Inherited Alzheimer Network, M. Edip Gurol, Mark A. van Buchem, Ralph Martins, Jasmeer P. Chhatwal, Steven M. Greenberg. Annals of Neurology 2019 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: , ,

Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity

Posted on August 27, 2019

Amber Tariq, JiaBei Lin, Meredith E. Jackrel, Christina D. Hesketh, Peter J. Carman, Korrie L. Mack, Rachel Weitzman, Craig Gambogi, Oscar A. Hernandez Murillo, Elizabeth A. Sweeny, Esin Gurpinar, Adam L. Yokom, Stephanie N. Gates, Keolamau Yee, Saurabh Sudesh, Jacob Stillman, Alexandra N. Rizo, Daniel R. Southworth, James Shorter. Cell Reports 2019 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

An endogenous peptide marker differentiates SOD1 stability and facilitates pharmacodynamic monitoring in SOD1 amyotrophic lateral sclerosis

Posted on August 27, 2019

Ilya Gertsman, Joanne Wuu, Melissa McAlonis-Downes, Majid Ghassemian, Karen Ling, Frank Rigo, Frank Bennett, Michael Benatar, Timothy M. Miller, and Sandrine Da Cruz. JCI Insight, Volume 4, Issue 10, 2019, Article number e122768 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, NeuroRestorative Therapy, Publications Faculty: