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A murine Niemann-Pick C1 (NPC1) I1061T knockin model recapitulates the pathological features of the most prevalent human disease allele

Posted on October 20, 2016

Praggastis M, Tortelli B, Zhang J, Fujiwara H, Sidhu R, Chacko A, Chen Z, Lieberman AP, Davidson C, Walkley SU, Pipalia NH, Maxfield FR, Schaffer JE, and Ory DS: 2015 J Neuroscience, 35:8091-8106. PMCID: PMC4444535 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Publications Faculty:

Contraction and stress-dependent growth shape the forebrain of the early chicken embryo

Posted on September 30, 2016

Garcia KE, Okamoto RJ, Bayly PV: 2017 Journal of the Mechanical Behavior of Biomedical Materials, vol 65, pp 383-397 Read More

Posted in: Axon Injury & Repair, Publications Faculty:

Focusing light through biological tissue and tissue-mimicking phantoms up to 9.6 cm in thickness with digital optical phase conjugation

Posted on September 30, 2016

Shen Y, Liu Y, Ma C, et al: 2016 Journal of Biomedical Optics, 21(8), art number 085001 Read More

Posted in: Neurovascular Injury & Repair, Publications Faculty:

Imaging and cerebrospinal fluid biomarkers in early preclinical alzheimer disease

Posted on September 30, 2016

Vlassenko AG, McCue L, Jasielec MS, et al: 2016 Annals of Neurology, 80(3), pp 379-387 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: , , ,

Inhibition of DNA methyltransferases blocks mutant huntingtin-induced neurotoxicity

Posted on August 31, 2016

Pan Y, Daito T, Sasaki Y, et al: 2016 Sci Rep doi: 10.1038/srep31022 Read More

Posted in: HPAN, Neurodegeneration, NeuroRestorative Therapy, Publications Faculty: ,