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C-terminal phosphorylation of NaV1.5 impairs FGF13-dependent regulation of channel inactivation

Posted on November 1, 2017

Sophie Burel, Fabien C. Coyan, Maxime Lorenzini, Matthew R. Meyer, Cheryl F. Lichti, Joan H. Brown, Gildas Loussouarn, Flavien Charpentier, Jeanne M. Nerbonne, R. Reid Townsend, Lars S. Maier and Céline Marionneau: Journal of Biological Chemistry, Volume 292, Issue 42, 2017, Pages 17431-17448 Read More

Posted in: Clocks & Sleep, Neurogenetics & Transcriptomics, Publications Faculty:

Monomeric Huntingtin Exon 1 Has Similar Overall Structural Features for Wild-Type and Pathological Polyglutamine Lengths

Posted on October 31, 2017

John B. Warner IV, Kiersten M. Ruff, Piau Siong Tan, Edward A. Lemke, Rohit V. Pappu, and Hilal A. Lashuel: J. Am. Chem. Soc., 2017, 139 (41), pp 14456–14469 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Peptide-Level Interactions between Proteins and Small-Molecule Drug Candidates by Two Hydrogen-Deuterium Exchange MS-Based Methods: The Example of Apolipoprotein E3

Posted on October 31, 2017

Hanliu Wang, Don L. Rempel, Daryl Giblin, Carl Frieden, and Michael L. Gross: 2017 Analytical Chemistry, Volume 89, Issue 20, 17 October, Pages 10687-10695 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Effect of simvastatin on CSF Alzheimer disease biomarkers in cognitively normal adults

Posted on October 25, 2017

Ge Li, Cynthia L. Mayer, Daniel Morelli, Steven P. Millard, Wendy H. Raskind, Eric C. Petrie, Monique Cherrier, Anne M. Fagan, Murray A. Raskind and Elaine R. Peskind: 2017 Neurology, Volume 89, Issue 12, 19 September, Pages 1251-1255 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

MicroRNAs Induce a Permissive Chromatin Environment that Enables Neuronal Subtype-Specific Reprogramming of Adult Human Fibroblasts

Posted on October 24, 2017

Daniel G. Abernathy, Woo Kyung Kim, Matthew J. McCoy, Allison M. Lake, Rebecca Ouwenga, Seong Won Lee, Xiaoyun Xing, Daofeng Li, Hyung Joo Lee, Robert O. Heuckeroth, Joseph D. Dougherty, Ting Wang, Andrew S. Yoo: 2017 Cell Stem Cell
Volume 21, Issue 3, Pages 332-348.e9 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, NeuroRestorative Therapy, Publications Faculty: ,