Posted in the category:

Pilot Projects

The self-association and stability of the apoe isoforms at low pH: implications for apoE-lipid interactions.

Posted on October 7, 2011

Garai K, Baban B, Frieden C (2011). Biochemistry, 50:6356-6364 Read More

Posted in: HPAN, Neurodegeneration, Pilot Projects, Publications Faculty:

Serotonin signaling is associated with lower amyloid-beta levels and plaques in transgenic mice and humans

Posted on October 6, 2011

Cirrito JR, Disabato BM, Restivo JL, Verges DK, Goebel WD, Sathyan A, Hayreh D, D’Angelo G, Benzinger T, Yoon H, Kim J, Morris JC, Mintun MA, Sheline YI (2011). Proc Natl Acad Sci USA, 108(36):14968-73 Read More

Posted in: HPAN, Neurodegeneration, Pilot Projects, Publications, Therapeutics & Diagnostics Faculty: , ,

Inter-protofilament interactions between Alzheimer’s ABeta1-42 peptides in amyloid fibrils revealed by cryo-EM

Posted on October 12, 2009

Zhang R, Hu X, Khant H, Ludtke SJ, Chiu W, Schmid MF, Frieden C, Lee JM (2009). Proc Natl Acad Sci USA, 106(12):4653-8 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, Neurovascular Injury & Repair, Pilot Projects, Publications Faculty: ,

Amyloid seeds formed by cellular uptake, concentration, and aggregation of the amyloid-beta peptide

Posted on October 12, 2009

Hu X, Crick SL, Bu G, Frieden C, Pappu RV, Lee JM (2009). Proc Natl Acad Sci USA, 106(48):20324-9 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, Neurovascular Injury & Repair, Pilot Projects, Publications Faculty: , ,