Posted in the category:

Neurogenetics & Transcriptomics

Protein linked to Alzheimer’s, strokes cleared from brain blood vessels

Posted on February 18, 2021

In mice, antibody removes amyloid, improves vessel function without raising risk of brain bleeds Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Neurovascular Injury & Repair, News Faculty: ,

Microglial activation elicits a negative affective state through prostaglandin-mediated modulation of striatal neurons

Posted on February 15, 2021

Anna M Klawonn, Michael Fritz , Silvia Castany, Marco Pignatelli, Carla Canal, Fredrik Similä, Hugo A Tejeda, Julia Levinsson, Maarit Jaarola Johan Jakobsson , Juan Hidalgo, Markus Heilig, Antonello Bonci, David Engblom. Immunity. 2021 Feb 9;54(2):225-234.e6. Read More

Posted in: Neurogenetics & Transcriptomics, Publications Faculty:

Aggressive brain tumor mapped in genetic, molecular detail

Posted on February 11, 2021

Glioblastoma study could lead to new treatments, including better immunotherapies Read More

Posted in: Neurogenetics & Transcriptomics, NeuroRestorative Therapy, News Faculty: ,

Modeling autosomal dominant Alzheimer’s disease with machine learning

Posted on February 8, 2021

Patrick H Luckett, Austin McCullough, Brian A Gordon, […] Carlos Cruchaga, Anne M Fagan, […], Richard J Perrin, Celeste M Karch, Jason Hassenstab, Eric McDade, John C Morris, Tammie L S Benzinger, Randall J Bateman, Beau M Ances, Dominantly Inherited Alzheimer Network (DIAN). Alzheimers Dementia. 2021 Jan 21. Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , , , , ,

Prior activation state shapes the microglia response to antihuman TREM2 in a mouse model of Alzheimer’s disease

Posted on February 8, 2021

Daniel C Ellwanger, Shoutang Wang, Simone Brioschi, […], Menno van Lookeren Campagne, Marco Colonna. PNAS January 19, 2021 118 (3) e2017742118 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: