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HPAN

Dural lymphatics regulate clearance of extracellular tau from the CNS

Posted on March 13, 2019

Tirth K. Patel, LeMoyne Habimana-Griffin, Xuefeng Gao, Baogang Xu, Samuel Achilefu, Kari Alitalo, Celia A. McKee, Patrick W. Sheehan, Erik S. Musiek, Chengjie Xiong, Dean Coble and David M. Holtzman. Molecular Neurodegeneration, Volume 14, Issue 1, 27 February 2019, Article number 11 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: ,

Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer’s disease

Posted on March 13, 2019

Suzanne E. Schindler, Yan Li, Kaitlin W. Todd, Elizabeth M. Herries, Rachel L. Henson, Julia D. Gray, Guoqiao Wang, Danielle L. Graham, Leslie M. Shaw, John Q. Trojanowski, Jason J. Hassenstab, Tammie L.S. Benzinger, Carlos Cruchaga, Mathias Jucker, Johannes Levin, Jasmeer P. Chhatwal, James M. Noble, John M. Ringman, Neill R. Graff-Radford, David M. Holtzman, Jack H. Ladenson, John C. Morris, Randall J. Bateman, Chengjie Xiong, Anne M. Fagan for the Dominantly Inherited Alzheimer Network. Alzheimer’s and Dementia 2019 Read More

Posted in: Clocks & Sleep, HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , ,

Repeated neonatal isoflurane exposures in the mouse induce apoptotic degenerative changes in the brain and relatively mild long-term behavioral deficits

Posted on March 13, 2019

Susan E. Maloney, Carla M. Yuede, Catherine E. Creeley, Sasha L. Williams, Jacob N. Huffman, George T. Taylor, Kevin N. Noguchi & David F. Wozniak. Scientific Reports, Volume 9, Issue 1, 1 December 2019, Article number 2779 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Structure of Calcarisporiella thermophila Hsp104 Disaggregase that Antagonizes Diverse Proteotoxic Misfolding Events

Posted on March 12, 2019

Karolina Michalska, Kaiming Zhang, Zachary M. March, Catherine Hatzos-Skintges, Grigore Pintilie, Lance Bigelow, Laura M. Castellano, Leann J. Miles, Meredith E. Jackrel, Edward Chuang, Robert Jedrzejczak, James Shorter, Wah Chiu, Andrzej Joachimiak. Structure, Volume 27, Issue 3, 5 March 2019, Pages 449-463.e7 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Impact of early diabetic ketoacidosis on the developing brain

Posted on March 7, 2019

Tandy Aye, Paul K. Mazaika, Nelly Mauras, Matthew J. Marzelli, Hanyang Shen, Tamara Hershey, Allison Cato, Stuart A. Weinzimer, Neil H. White, Eva Tsalikian, Booil Jo and Allan L. Reiss, for the Diabetes Research in Children Network (DirecNet) Study Group. Diabetes Care, Volume 42, Issue 3, 1 March 2019, Pages 443-449 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: