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TREM2 deficiency attenuates neuroinflammation and protects against neurodegeneration in a mouse model of tauopathy

Posted on November 11, 2017

Cheryl E. G. Leyns, Jason D. Ulrich, Mary B. Finn, Floy R. Stewart, Lauren J. Koscal, Javier Remolina Serrano, Grace O. Robinson, Elise Anderson, Marco Colonna, and David M. Holtzman,: Proceedings of the National Academy of Sciences of the United States of America, Volume 114, Issue 43, 24 October 2017, Pages 11524-11529 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: ,

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Posted on November 7, 2017

Lei Du, Kefei Liu, Xiaohui Yao, Jingwen Yan, Shannon L. Risacher, Junwei Han, Lei Guo, Andrew J. Saykin, Li Shen & Alzheimer’s Disease Neuroimaging Initiative: Scientific Reports, Volume 7, Issue 1, 1 December 2017, Article number 14052 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration Faculty: , , , , ,

Data quality influences observed links between functional connectivity and behavior

Posted on November 7, 2017

Joshua S. Siegel Anish Mitra Timothy O. Laumann Benjamin A. Seitzman Marcus Raichle Maurizio Corbetta Abraham Z. Snyder: Cerebral Cortex, Volume 27, Issue 9, 2017, Pages 4492-4502 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Functional connectivity structure of cortical calcium dynamics in anesthetized and awake mice

Posted on November 3, 2017

Patrick W. Wright, Lindsey M. Brier, Adam Q. Bauer, Grant A. Baxter, Andrew W. Kraft, Matthew D. Reisman, Annie R. Bice, Abraham Z. Snyder, Jin-Moo Lee, Joseph P. Culver: PLoS ONE, Volume 12, Issue 10, October 2017, Article number e0185759 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics Faculty:

The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

Posted on November 2, 2017

Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno,…et al.: Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: