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Amyloid-β Plaques in clinical Alzheimer’s disease brain incorporate stable isotope tracer in vivo and exhibit nanoscale heterogeneity

Posted on April 4, 2018

Norelle C. Wildburger, Frank Gyngard, Christelle Guillermier, Bruce W. Patterson, Donald Elbert, Kwasi G. Mawuenyega, Theresa Schneider, Karen Green, Robyn Roth, Robert E. Schmidt, Nigel J. Cairns, Tammie L. S. Benzinger, Matthew L. Steinhauser, Randall J. Bateman. Frontiers in Neurology, Volume 9, Issue MAR, 22 March 2018, Article number 169 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , ,

Alzheimer’s disease and sleep–wake disturbances: Amyloid, astrocytes, and animal models

Posted on April 4, 2018

William M. Vanderheyden, Miranda M. Lim, Erik S. Musiek and Jason R. Gerstner. Journal of Neuroscience, Volume 38, Issue 12, 21 March 2018, Pages 2901-2910 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty:

Tau Kinetics in Neurons and the Human Central Nervous System

Posted on April 2, 2018

Chihiro Sato, Nicolas R. Barthélemy, Kwasi G. Mawuenyega, Bruce W. Patterson, Brian A. Gordon, Jennifer Jockel-Balsarotti, Melissa Sullivan, Matthew J. Crisp, Tom Kasten, Kristopher M. Kirmess, Nicholas M. Kanaan, Kevin E. Yarasheski, Alaina Baker-Nigh, Tammie L.S. Benzinger, Timothy M. Miller, Celeste M. Karch, Randall J. Bateman. Neuron, Volume 97, Issue 6, 21 March 2018, Pages 1284-1298.e7 Read More

Posted in: Axon Injury & Repair, Clocks & Sleep, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, NeuroRestorative Therapy, Publications Faculty: , , ,

Slow, steady waves keep brain humming

Posted on March 29, 2018

Such rhythmic waves linked to state of consciousness Read More

Posted in: HPAN, Neurodegeneration, News Faculty:

Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers

Posted on March 28, 2018

Ammon E. Posey, Kiersten M. Ruff, Tyler S. Harmon, Scott L. Crick, Aimin Li, Marc I. Diamond and Rohit V. Pappu. Journal of Biological Chemistry, Volume 293, Issue 10, 2018, Pages 3734-3746 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: ,