Publications

The latest published manuscripts and reviews from Hope Center investigators, and publications based on use of Hope Center Cores. Click on titles to learn more. Read More

Heparan sulfate proteoglycans mediate Aβ-induced oxidative stress and hypercontractility in cultured vascular smooth muscle cells

Posted on November 9, 2016

Reynolds, Matthew R., Itender Singh, Tej D. Azad, Brandon B. Holmes, Phillip B. Verghese, Hans H. Dietrich, Marc Diamond, Guojun Bu, Byung Hee Han, and Gregory J. Zipfel: 2016 Molecular Neurodegeneration 11, no. 1:1. Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Neurovascular Injury & Repair, Publications Faculty: ,

Clinically early-stage CSPα mutation carrier exhibits remarkable terminal stage neuronal pathology with minimal evidence of synaptic loss

Posted on October 20, 2016

Benitez BA, Cairns NJ, Schmidt RE, Morris JC, Norton JB, Cruchaga C, Sands MS. Acta Neuropathol Commun. 2015 Nov 26;3:73. PMID: 26610600 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics, Publications Faculty: , , ,

Maintenance of age in human neurons generated by microRNA-based neuronal conversion of fibroblasts

Posted on October 20, 2016

Christine J Huh Bo Zhang Matheus B Victor Sonika Dahiya Luis FZ Batista Steve Horvath Andrew S Yoo: 2016 eLife;5:e18648. DOI: http://dx.doi.org/10.7554/eLife.18648 Read More

Posted in: HPAN, Neurodegeneration, NeuroRestorative Therapy, Publications Faculty:

The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging

Posted on October 20, 2016

Brian A. Gordon, Karl Friedrichsen, Matthew Brier, Tyler Blazey, Yi Su, Jon Christensen, Patricia Aldea, Jonathan McConathy, David M. Holtzman, Nigel J. Cairns, John C. Morris, Anne M. Fagan, Beau M. Ances and Tammie L. S. Benzinger: 2016 Brain, doi:10.1093/brain/aww139 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: , , , ,

Tau and Ab imaging, CSF measures, and cognition in Alzheimer’s disease

Posted on October 20, 2016

Matthew R. Brier, Brian Gordon, Karl Friedrichsen, John McCarthy, Ari Stern, Jon Christensen, Christopher Owen, Patricia Aldea, Yi Su, Jason Hassenstab, Nigel J. Cairns, David M. Holtzman, Anne M. Fagan, John C. Morris, Tammie L. S. Benzinger, Beau M. Ances: 2016 Science Translational Medicine, 8(338). Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty: , , , ,