News & Publications for:

Alison Goate

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: A genome-wide association study

Posted on January 8, 2015

Adam C. Naj, PhD; Gyungah Jun, PhD; Christiane Reitz, MD, PhD; Brian W. Kunkle, PhD; William Perry, MPH; Yo Son Park, BS; Gary W. Beecham, PhD; Ruchita A. Rajbhandary, MPH; Kara L. Hamilton-Nelson, MPH; Li-San Wang, PhD; John S. K. Kauwe, PhD; Matthew J. Huentelman, PhD; Amanda J. Myers, PhD; Thomas D. Bird, MD; Bradley F. Boeve, MD; Clinton T. Baldwin, PhD; Gail P. Jarvik, MD, PhD; Paul K. Crane, MD, MPH; Ekaterina Rogaeva, PhD; M. Michael Barmada, PhD; F. Yesim Demirci, MD; Carlos Cruchaga, PhD; Patricia L. Kramer, PhD; Nilufer Ertekin-Taner, MD, PhD; John Hardy, PhD; Neill R. Graff-Radford, MD; Robert C. Green, MD, MPH; Eric B. Larson, MD, MPH; Peter H. St. George-Hyslop, MD, FRCP; Joseph D. Buxbaum, PhD; Denis A. Evans, MD; Julie A. Schneider, MD; Kathryn L. Lunetta, PhD; M. Ilyas Kamboh, PhD; Andrew J. Saykin, PsyD; Eric M. Reiman, MD; Philip L. De Jager, MD, PhD; David A. Bennett, MD; John C. Morris, MD; Thomas J. Montine, MD, PhD; Alison M. Goate, DPhil; Deborah Blacker, MD; Debby W. Tsuang, MD; Hakon Hakonarson, MD, PhD; Walter A. Kukull, PhD; Tatiana M. Foroud, PhD; Eden R. Martin, PhD; Jonathan L. Haines, PhD; Richard P. Mayeux, MD; Lindsay A. Farrer, PhD; Gerard D. Schellenberg, PhD; Margaret A. Pericak-Vance, PhD2; and the Alzheimer Disease Genetics Consortium; 2014 JAMA Neurology Vol 71 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics Faculty: , , ,

Genetic influences on alcohol use across stages of development: GABRA2 and longitudinal trajectories of drunkenness from adolescence to young adulthood

Posted on January 8, 2015

Danielle M. Dick, Seung Bin Cho, Shawn J. Latendresse, Fazil Aliev, John I. Nurnberger Jr, Howard J. Edenberg, Marc Schuckit, Victor M. Hesselbrock, Bernice Porjesz, Kathleen Bucholz, Jen-Chyong Wang, Alison Goate, John R. Kramer and Samuel Kuperman; 2014 Addiction Biology, Volume 19, Issue 6, November 2014, Pages: 1055–1064 Read More

Posted in: Neurogenetics, Publications Faculty:

Beyond cigarettes per day: A genome-wide association study of the biomarker carbon monoxide

Posted on December 11, 2014

A. Joseph Bloom, Sarah M. Hartz, Timothy B. Baker, Li-Shiun Chen, Megan E. Piper, Louis Fox, Maribel Martinez, Dorothy Hatsukami, Eric O. Johnson, Cathy C. Laurie, Nancy L. Saccone, Alison Goate, Laura J. Bierut; 2014, Annals of the American Thoracic Society, 11(7), p1003-1010 Read More

Posted in: Neurogenetics, Publications Faculty:

Alzheimer’s therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity

Posted on December 11, 2014

Nicholas J. Izzo, Jinbin Xu, Chenbo Zeng, Molly J. Kirk, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Gary Look, Gilbert Rishton,Hank Safferstein, Carlos Cruchaga, Alison Goate, Michael A. Cahill, Ottavio Arancio, Robert H. Mach, Rolf Craven, Elizabeth Head, Harry LeVine III,Tara L. Spires-Jones, Susan M. Catalano; 2014, PLoS ONE, 9(11), Article number e111899 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, Publications Faculty: ,

Coding variants in TREM2 increase risk for Alzheimer’s disease

Posted on December 11, 2014

Sheng Chih Jin, Bruno A. Benitez, Celeste M. Karch, Breanna Cooper, Tara Skorupa, David Carrell, Joanne B. Norton, Simon Hsu, Oscar Harari, Yefei Cai, Sarah Bertelsen, Alison M. Goate, and Carlos Cruchaga; 2014, Human Molecular Genetics, 23(21), p5835-5846 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics, Publications Faculty: , ,