News & Publications for:

Carl Frieden

Native Mass Spectrometry, Ion Mobility, Electron-Capture Dissociation, and Modeling Provide Structural Information for Gas-Phase Apolipoprotein E Oligomers

Posted on May 30, 2019

Hanliu Wang, Joseph Eschweiler, Weidong Cui, Hao Zhang, Carl Frieden, Brandon T. Ruotolo, Michael L. Gross. Journal of the American Society for Mass Spectrometry, Volume 30, Issue 5, 1 May 2019, Pages 876-885 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Protein oligomerization as a metabolic control mechanism: Application to apoE

Posted on March 6, 2019

Carl Frieden. Protein Science 2019 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Structure-function analysis of the curli accessory protein CsgE defines surfaces essential for coordinating amyloid fiber formation

Posted on November 7, 2018

Roger D. Klein, Qin Shu, Zachary T. Cusumano, Kanna Nagamatsu, Nathaniel C. Gualberto, Aaron J. L. Lynch, Chao Wu, Wenjie Wang, Neha Jain, Jerome S. Pinkner, Gaya K. Amarasinghe, Scott J. Hultgren, Carl Frieden, Matthew R. Chapman. mBio, Volume 9, Issue 4, July-August 2018, Article number e01349-18 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Peptide-Level Interactions between Proteins and Small-Molecule Drug Candidates by Two Hydrogen-Deuterium Exchange MS-Based Methods: The Example of Apolipoprotein E3

Posted on October 31, 2017

Hanliu Wang, Don L. Rempel, Daryl Giblin, Carl Frieden, and Michael L. Gross. 2017 Analytical Chemistry, Volume 89, Issue 20, 17 October, Pages 10687-10695 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Deamidation Slows Curli Amyloid-Protein Aggregation

Posted on July 10, 2017

Hanliu Wang, Qin Shu, Carl Frieden, and Michael L. Gross: 2017 Biochemistry Volume 56, Issue 23, 13, Pages 2865-2872 Read More

Posted in: HPAN, Neurodegeneration Faculty: