News & Publications for:

Carlos Cruchaga

TREM2 is associated with increased risk for Alzheimer’s disease in African Americans

Posted on May 21, 2015

Jin SC, Carrasquillo MM, Benitez BA, et al: 2015 Molecular Neurodegeneration Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, Publications Faculty: ,

The influence of genetic variants in SORL1 gene on the manifestation of Alzheimer’s disease

Posted on March 12, 2015

Eva Louwersheimer, Alfredo Ramirez, Carlos Cruchaga, et al: 2015 Neurobiology of Aging, 36(3) pp1605.e13-e20 Read More

Posted in: HPAN, Lysosome, Neurogenetics, Publications Faculty:

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: A genome-wide association study

Posted on January 8, 2015

Adam C. Naj, PhD; Gyungah Jun, PhD; Christiane Reitz, MD, PhD; Brian W. Kunkle, PhD; William Perry, MPH; Yo Son Park, BS; Gary W. Beecham, PhD; Ruchita A. Rajbhandary, MPH; Kara L. Hamilton-Nelson, MPH; Li-San Wang, PhD; John S. K. Kauwe, PhD; Matthew J. Huentelman, PhD; Amanda J. Myers, PhD; Thomas D. Bird, MD; Bradley F. Boeve, MD; Clinton T. Baldwin, PhD; Gail P. Jarvik, MD, PhD; Paul K. Crane, MD, MPH; Ekaterina Rogaeva, PhD; M. Michael Barmada, PhD; F. Yesim Demirci, MD; Carlos Cruchaga, PhD; Patricia L. Kramer, PhD; Nilufer Ertekin-Taner, MD, PhD; John Hardy, PhD; Neill R. Graff-Radford, MD; Robert C. Green, MD, MPH; Eric B. Larson, MD, MPH; Peter H. St. George-Hyslop, MD, FRCP; Joseph D. Buxbaum, PhD; Denis A. Evans, MD; Julie A. Schneider, MD; Kathryn L. Lunetta, PhD; M. Ilyas Kamboh, PhD; Andrew J. Saykin, PsyD; Eric M. Reiman, MD; Philip L. De Jager, MD, PhD; David A. Bennett, MD; John C. Morris, MD; Thomas J. Montine, MD, PhD; Alison M. Goate, DPhil; Deborah Blacker, MD; Debby W. Tsuang, MD; Hakon Hakonarson, MD, PhD; Walter A. Kukull, PhD; Tatiana M. Foroud, PhD; Eden R. Martin, PhD; Jonathan L. Haines, PhD; Richard P. Mayeux, MD; Lindsay A. Farrer, PhD; Gerard D. Schellenberg, PhD; Margaret A. Pericak-Vance, PhD2; and the Alzheimer Disease Genetics Consortium; 2014 JAMA Neurology Vol 71 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics Faculty: , , ,

Alzheimer’s therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity

Posted on December 11, 2014

Nicholas J. Izzo, Jinbin Xu, Chenbo Zeng, Molly J. Kirk, Kelsie Mozzoni, Colleen Silky, Courtney Rehak, Raymond Yurko, Gary Look, Gilbert Rishton,Hank Safferstein, Carlos Cruchaga, Alison Goate, Michael A. Cahill, Ottavio Arancio, Robert H. Mach, Rolf Craven, Elizabeth Head, Harry LeVine III,Tara L. Spires-Jones, Susan M. Catalano; 2014, PLoS ONE, 9(11), Article number e111899 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, Publications Faculty: ,