News & Publications for:

Carlos Cruchaga

Same genes linked to early- and late-onset Alzheimer’s

Posted on February 2, 2012

Next generation sequencing of dementia genes in families touched by Alzheimer’s. Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, News Faculty: ,

Researchers identify gene for rare dementia

Posted on December 16, 2011

Cruchaga and colleagues identify DNAJC5 variants in Kufs disease, a neurodegenerative disorder in the neuronal ceroid lipofuscinoses (NCL) family. Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, News, Pilot Projects Faculty: , , ,

Exome-Sequencing Confirms DNAJC5 Mutations as Cause of Adult Neuronal Ceroid-Lipofuscinosis

Posted on November 9, 2011

Benitez BA, Alvarado D, Cai Y, Mayo K, Chakraverty S, Norton J, Morris JC, Sands MS, Goate AM, Cruchaga C (2011). PLoS One, 6(11):e26741 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, Pilot Projects, Publications, Therapeutics & Diagnostics Faculty: , ,

Human apoE isoforms differentially regulate brain amyloid-beta peptide clearance

Posted on October 12, 2011

Castellano JM, Kim J, Stewart FR, Jiang H, DeMattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C, Goate AM, Bales KR, Paul SM, Bateman RJ, Holtzman DM (2011). Science Translational Medicine, 3(89):89ra57 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, Publications, Therapeutics & Diagnostics Faculty: , , , , , ,

Association of TMEM106B gene polymorphism with age at onset in granulin mutation carriers and plasma granulin protein levels

Posted on October 11, 2011

Cruchaga C, Graff C, Chiang HH, Wang J, Hinrichs AL, Spiegel N, Bertelsen S, Mayo K, Norton JB, Morris JC, Goate AM (2011). Arch Neurol, 68(5):581-6. PMCID:3090529 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, Publications, Therapeutics & Diagnostics Faculty: , ,