News & Publications for:

Daniel Ory

Cholesterol oxidation products are sensitive and specific blood-based biomarkers for Niemann-Pick C1 disease

Posted on October 13, 2010

Porter FD, Scherrer DE, Lanier MH, Langmade SJ, Molugu V, Gale SE, Olzeski D, Sidhu R, Dietzen DJ, Fu R, Wassif CA, Yanjanin NM, Marso SP, House J, Vite C, Schaffer JE, Ory DS (2010). Sci Transl Med, 2(56):56ra81
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Posted in: HPAN, Neurodegeneration, Publications Faculty:

NPC1 I1061T mutant encodes a functional protein that is selected for ER-associated degradation due to protein misfolding

Posted on October 13, 2008

Gelsthorpe ME, Baumann N, Millard E, Gale SE, Langmade SJ, Schaffer JE, Ory DS (2008). J Biol Chem, 283(13):8229-36
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Posted in: HPAN, Neurodegeneration, Publications Faculty:

Niemann-Pick C1 protects against atherosclerosis in mice via regulation of macrophage intracellular cholesterol trafficking

Posted on October 13, 2008

Zhang JR, Coleman T, Langmade SJ, Scherrer DE, Lane L, Lanier MH, Feng C, Sands MS, Schaffer JE, Semenkovich CF, Ory DS (2008). J Clin Invest, 118(6):2281-90
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Posted in: HPAN, Neurodegeneration, Publications Faculty:

The sterol-sensing domain of the Niemann-Pick C1 (NPC1) protein regulates trafficking of low-density lipoprotein cholesterol

Posted on October 13, 2005

Millard EE, Gale SE, Dudley N, Zhang J, Schaffer JE, Ory DS (2005). J Biol Chem, 280(31):28581-90
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Posted in: HPAN, Neurodegeneration, Publications Faculty: