News & Publications for:

David Holtzman

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Posted on November 7, 2017

Lei Du, Kefei Liu, Xiaohui Yao, Jingwen Yan, Shannon L. Risacher, Junwei Han, Lei Guo, Andrew J. Saykin, Li Shen & Alzheimer’s Disease Neuroimaging Initiative: Scientific Reports, Volume 7, Issue 1, 1 December 2017, Article number 14052 Read More

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The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases

Posted on November 2, 2017

Susanne Krasemann, Charlotte Madore, Ron Cialic, Caroline Baufeld, Narghes Calcagno,…et al.: Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty:

Antibody therapeutics targeting Aβ and tau

Posted on October 19, 2017

Gilbert Gallardo and David M. Holtzman: 2017 Cold Spring Harbor Perspectives in Medicine, Volume 7, Issue 10, Article number a024331 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Publications Faculty:

Alzheimer’s gene poses both risk — and benefits

Posted on October 10, 2017

Study suggests role of inflammation in brain disease is complicated Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, News Faculty: ,

Lack of BACE1 S-palmitoylation reduces amyloid burden and mitigates memory deficits in transgenic mouse models of Alzheimer’s disease

Posted on September 30, 2017

Robert J. Andrewa, […], David M. Holtzman and Gopal Thinakaran: Proceedings of the National Academy of Sciences of the United States of America, Volume 114, Issue 45, 7 November 2017, Pages E9665-E9674 Read More

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