News & Publications for:

David Holtzman

Phosphorylated tau-Aβ42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimer’s disease in multiplex immunoassay panels of cerebrospinal fluid

Posted on May 19, 2014

Harari O, Cruchaga C, Kauwe JSK, Ainscough BJ, Bales K, Pickering EH, Bertelsen S, Fagan AM, Holtzman DM, Morris JC, Goate AM; Biological Psychiatry 75(9); pp 723-731 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, Publications Faculty: , , , ,

Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer’s disease

Posted on April 24, 2014

Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benziger TLS, Ghetti B, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Salloway S, Schofield PR, Sperling RA, Marcus D, Cairns NJ, Buckles VD, Ladenson JH, Morris JC; 2014 Science Translational Medicine, 6 (226), art. no. 226ra30 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, Publications Faculty: , , , , ,

Neuronal Activity regulates extracellular tau in vivo

Posted on April 10, 2014

Kaoru Yamada, Jarrah Holth, Fan Liao, Floy Stewart, Thomas Mahan, Hong Jiang, John Cirrito, Tirth Patel, Katja Hochgrafe, Eva-Maria Madelkow, David Holtzman; 2014 JEM 211(3) pp 387-393 Read More

Posted in: HPAN, Neurodegeneration, Neurovascular Injury & Repair, Publications Faculty: ,