News & Publications for:

John Cirrito

John Cirrito‘s Faculty Page

Genetic suppression of transgenic APP rescues hypersynchronous network activity in a mouse model of alzeimer’s disease

Posted on April 10, 2014

Born H, Kim J-Y, Savjani R, Pritam D, Dabaghian Y, Guo Q, Yoo J, Schuler D, Cirrito J, Zheng H, Golde T, Noebels J, Jankowsky J; Journal of Neuroscience 34(11) pp 3826-3840 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty:

Neuronal Activity regulates extracellular tau in vivo

Posted on April 10, 2014

Kaoru Yamada, Jarrah Holth, Fan Liao, Floy Stewart, Thomas Mahan, Hong Jiang, John Cirrito, Tirth Patel, Katja Hochgrafe, Eva-Maria Madelkow, David Holtzman; 2014 JEM 211(3) pp 387-393 Read More

Posted in: HPAN, Neurodegeneration, Neurovascular Injury & Repair, Publications Faculty: ,

Attenuating astrocyte activation accelerates plaque pathogenesis and neurotoxicity in APP/PS1 mice

Posted on January 30, 2014

Kraft, A. W., Hu, X., Yoon, H., Yan, P., Xiao, Q., Wang, Y., Gil, S. C., Brown, J., Wilhelmsson, U., Restivo, J. L., Cirrito, J. R., Holtzman, D. M., Kim, J., Pekny, M., Lee, J.-M.; FASEB J, 27(1): 187-98 2012 Read More

Posted in: HPAN, Neurogenetics, Neurovascular Injury & Repair, Publications Faculty: , ,

Role of Phosphatidylinositol Clathrin Assembly Lymphoid-Myeloid Leukemia (PICALM) in intracellular Amyloid Precursor Protein (APP) Processing and Amyloid Plaque Pathogenesis.

Posted on January 30, 2014

Xiao Q, Gil SC, Yan P, Wang Y, Han S, Gonzales E, Perez R, Cirrito JR, Lee J-M; J Biol Chem, 287 (1): 187-98, 2012 Read More

Posted in: HPAN, Neurogenetics, Neurovascular Injury & Repair, Publications Faculty: ,

Antisense reduction of tau in adult mice protects against seizures

Posted on August 8, 2013

DeVos, S.L., Goncharoff, D.K., Chen, G., Kebodeaux, C.S., Yamada, K., Stewart, F.R., Schuler, D.R., Maloney, S.E., Wozniak, D.F., Rigo, F., Bennett, C.F., Cirrito, J.R., Holtzman, D.M., Miller, T.M.; (2013) Journal of Neuroscience, 33 (31), pp. 12887-12897. Read More

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