Characterizing the appearance and growth of amyloid plaques in APP/PS1 mice
Yan P, Bero AW, Cirrito JR, Xiao Q, Hu X, Wang Y, Gonzales E, Holtzman DM, Lee JM (2009). J Neurosci, 29(34):10706-14 Read More
News & Publications for:
John Cirrito
Amyloid-beta dynamics are regulated by orexin and the sleep-wake cycle
Kang JE, Lim MM, Bateman RJ, Lee JJ, Smyth LP, Cirrito JR, Fujiki N, Nishino S, Holtzman DM (2009). Science, 326:1005-1008 Read More
Posted in: HPAN, Neurodegeneration, Neurogenetics, Publications, Therapeutics & Diagnostics
Faculty: David Holtzman, John Cirrito, Randall Bateman
Cerebrovascular dysfunction in amyloid precursor protein transgenic mice: contribution of soluble and insoluble amyloid-beta peptide, partial restoration via gamma-secretase inhibition
Han BH, Zhou ML, Abousaleh F, Brendza RP, Dietrich HH, Koenigsknecht-Talboo J, Cirrito JR, Milner E, Holtzman DM, Zipfel GJ (2008). J Neurosci, 28(50):13542-50. PMID:19074028 Read More
Endocytosis is required for synaptic activity-dependent release of amyloid-beta in vivo
Cirrito JR, Kang JE, Lee J, Stewart FR, Verges DK, Silverio LM, Bu G, Mennerick S, Holtzman DM (2008). Neuron, 58(1):42-51 Read More
Posted in: HPAN, Neurodegeneration, Publications, Therapeutics & Diagnostics
Faculty: David Holtzman, John Cirrito, Steven Mennerick
Synaptic activity regulates interstitial fluid amyloid-beta levels in vivo
Cirrito JR, Yamada KA, Finn MB, Sloviter RS, Bales KR, May PC, Schoepp DD, Paul SM, Mennerick S, Holtzman DM (2005). Neuron, 48(6):913-22 Read More
Posted in: HPAN, Neurodegeneration, Publications, Therapeutics & Diagnostics
Faculty: David Holtzman, John Cirrito, Kelvin Yamada, Steven Mennerick
