News & Publications for:

Nigel Cairns

Amyloid-β Plaques in clinical Alzheimer’s disease brain incorporate stable isotope tracer in vivo and exhibit nanoscale heterogeneity

Posted on April 4, 2018

Norelle C. Wildburger, Frank Gyngard, Christelle Guillermier, Bruce W. Patterson, Donald Elbert, Kwasi G. Mawuenyega, Theresa Schneider, Karen Green, Robyn Roth, Robert E. Schmidt, Nigel J. Cairns, Tammie L. S. Benzinger, Matthew L. Steinhauser, Randall J. Bateman. Frontiers in Neurology, Volume 9, Issue MAR, 22 March 2018, Article number 169 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , ,

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Posted on November 7, 2017

Lei Du, Kefei Liu, Xiaohui Yao, Jingwen Yan, Shannon L. Risacher, Junwei Han, Lei Guo, Andrew J. Saykin, Li Shen & Alzheimer’s Disease Neuroimaging Initiative: Scientific Reports, Volume 7, Issue 1, 1 December 2017, Article number 14052 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration Faculty: , , , , ,

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer’s disease

Posted on October 23, 2017

Rebecca Sims, Sven J van der Lee, Adam C Naj, Céline Bellenguez, Nandini Badarinarayan, Johanna Jakobsdottir, Brian W Kunkle, et al: 2017 Nature Genetics Volume 49, Issue 9, 1 September 2017, Pages 1373-1384 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: ,

Diversity of Amyloid-beta Proteoforms in the Alzheimer’s Disease Brain

Posted on September 6, 2017

Norelle C. Wildburger, Thomas J. Esparza, Richard D. LeDuc, Ryan T. Fellers, Paul M. Thomas, Nigel J. Cairns, Neil L. Kelleher, Randall J. Bateman & David L. Brody: 2017 Scientific Reports 7, Article number: 9520 Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, NeuroRestorative Therapy, Publications Faculty: , ,

AV-1451 PET imaging of tau pathology in preclinical Alzheimer disease: Defining a summary measure

Posted on September 6, 2017

Shruti Mishra, Brian A. Gordon, Yi Su, Jon Christensen, Karl Friedrichsen, Kelley Jackson, Russ Hornbeck, David A. Balota, Nigel J. Cairns, John C. Morris, Beau M. Ances, Tammie L. S. Benzinger: 2017 NeuroImage, Volume 161, 1 November 2017, Pages 171-178 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: , ,