News & Publications for:

Nigel Cairns

Genetic variants associated with Alzheimer’s disease confer different cerebral cortex cell-type population structure

Posted on June 15, 2018

Zeran Li, Jorge L. Del-Aguila, Umber Dube, John Budde, Rita Martinez, Kathleen Black, Qingli Xiao, Nigel J. Cairns, … Joseph D. Dougherty, Jin-Moo Lee, John C. Morris, Randall J. Bateman, Celeste M. Karch, Carlos Cruchaga and Oscar Harari. Genome Medicine, Volume 10, Issue 1, 8 June 2018, Article number 43 Read More

Posted in: HPAN, Lysosome, Neurodegeneration, Neurogenetics & Transcriptomics, Neurovascular Injury & Repair, Publications Faculty: , , , , , ,

Preferential degradation of cognitive networks differentiates Alzheimer’s disease from ageing

Posted on May 30, 2018

Jasmeer P Chhatwal Aaron P Schultz Keith A Johnson Trey Hedden Sehily Jaimes Tammie L S Benzinger Clifford Jack, Jr Beau M Ances John M Ringman Daniel S Marcus… Brain, Volume 141, Issue 5, 1 May 2018, Pages 1486-1500 Read More

Posted in: HPAN, Neurodegeneration, Publications Faculty: , , ,

White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer’s disease

Posted on May 25, 2018

Seonjoo Lee, Molly E. Zimmerman, Atul Narkhede, Sara E. Nasrabady, Giuseppe Tosto, Irene B. Meier, Tammie L. S. Benzinger, Daniel S. Marcus, Anne M. Fagan, Nick C. Fox, Nigel J. Cairns, David M. Holtzman, Virginia Buckles, [ … ], Dominantly Inherited Alzheimer Network. PLoS ONE, Volume 13, Issue 5, May 2018, Article number e0195838 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , , , ,

Amyloid-β Plaques in clinical Alzheimer’s disease brain incorporate stable isotope tracer in vivo and exhibit nanoscale heterogeneity

Posted on April 4, 2018

Norelle C. Wildburger, Frank Gyngard, Christelle Guillermier, Bruce W. Patterson, Donald Elbert, Kwasi G. Mawuenyega, Theresa Schneider, Karen Green, Robyn Roth, Robert E. Schmidt, Nigel J. Cairns, Tammie L. S. Benzinger, Matthew L. Steinhauser, Randall J. Bateman. Frontiers in Neurology, Volume 9, Issue MAR, 22 March 2018, Article number 169 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics & Transcriptomics, Publications Faculty: , ,

Pattern Discovery in Brain Imaging Genetics via SCCA Modeling with a Generic Non-convex Penalty

Posted on November 7, 2017

Lei Du, Kefei Liu, Xiaohui Yao, Jingwen Yan, Shannon L. Risacher, Junwei Han, Lei Guo, Andrew J. Saykin, Li Shen & Alzheimer’s Disease Neuroimaging Initiative: Scientific Reports, Volume 7, Issue 1, 1 December 2017, Article number 14052 Read More

Posted in: Clocks & Sleep, HPAN, Neurodegeneration Faculty: , , , , ,