News & Publications for:

Nigel Cairns

C9orf72 hexanucleotide repeat expansions in clinical alzheimer disease

Posted on June 19, 2013

Harms, M., Benitez, B.A., Cairns, N., Cooper, B., Cooper, P., Mayo, K., Carrell, D., Faber, K., Williamson, J.g , Bird, T.h , Diaz-Arrastia, R.i , Foroud, T.M.f , Boeve, B.F.j , Graff-Radford, N.R., Mayeux, R., Chakraverty, S., Goate, A.M., Cruchaga, C.;(2013) JAMA Neurology, 70 (6), pp. 736-741. Read More

Posted in: HPAN, Neurogenetics, Publications Faculty: , , ,

Clue to Alzheimer’s cause found in brain samples

Posted on October 24, 2012

David Brody and colleagues identify ratio of amyloid beta oligomers to plaques as a marker for dementia Read More

Posted in: Axon Injury & Repair, HPAN, Neurodegeneration, News Faculty: , , , ,

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer’s Disease

Posted on July 13, 2012

Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, Aisen PS, Ghetti B, Klunk WE, McDade E, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Schofield PR, Sperling RA, Salloway S, Morris JC; the Dominantly Inherited Alzheimer Network (2012). N Engl J Med, Epub Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, Publications, Therapeutics & Diagnostics Faculty: , , , , ,

National institute on aging-Alzheimer’s association guidelines for the neuropathologic assessment of Alzheimer’s disease: A practical approach

Posted on June 1, 2012

Montine TJ, Phelps CH, Beach TG, Bigio EH, Cairns NJ, Dickson DW, Duyckaerts C, Frosch MP, Masliah E, Mirra SS, Nelson PT, Schneider JA, Thal DR, Trojanowski JQ, Vinters HV, Hyman BT (2012). Acta Neuropathol, 123(1):1-11 Read More

Posted in: Neurodegeneration, Publications, Therapeutics & Diagnostics Faculty:

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer’s disease

Posted on October 11, 2011

Naj AC, … Goate AM, Blacker D, Tsuang DW, Hakonarson H, Kukull WA, Foroud TM, Haines JL, Mayeux R, Pericak-Vance MA, Farrer LA, Schellenberg GD (2011). Nat Genet, 43(5):436-41. PMCID:3090745 Read More

Posted in: HPAN, Neurodegeneration, Neurogenetics, Publications, Therapeutics & Diagnostics Faculty: , , ,