Pilot project guidelines

2013 Deadlines
Letter of intent: Wednesday, August 28
Submission: Thursday, September 19 Read More


Hope Center Pilot Awards advance the translational neuroscience goals of the Hope Center. Faculty may request up to $100,000 for two-year projects. Projects must involve at least two collaborating laboratories.  Each collaborating investigator should have a significant role in the project, and funds must be shared by at least two collaborating labs.  The Project PI must be a Hope Center faculty member; other collaborators and co-investigators are not required to be Hope Center members.  Each proposed project must be in a pilot phase and not a continuation of an existing project.  Projects will be reviewed by an independent faculty committee that will consider scientific merit, innovation, importance for future application to human nervous system disease, potential for external funding, and ability to advance the overall goals of the Hope Center.  Final decisions on funding will be made by the Hope Center Steering Committee based on recommendations of the Review Committee as well as programmatic considerations.

Award recipients commit to serving on a Hope Center pilot application review committee at least once within three years of the award.

Examples of topics that are eligible for funding include

  • Protein Folding and Neurodegeneration
  • Axonal Injury and Repair
  • Neurogenetics
  • Neurovascular Injury and Repair

This list is not exhaustive; other topics will be considered.  All proposals must be consistent with the Hope Center mission:

To improve the lives of people living with neurological disorders, through collaborative research that aims to discover fundamental mechanisms of neurodegeneration and repair, and translate that new understanding into cures and treatments.

Hope Center Pilot Projects – Application Instructions

Letter of Intent

• Name of project PI
• Name(s) of collaborators
• Brief description of project (1-3 sentences)
• Brief description of the approach/system to be used

Complete application in the form of a single pdf

• Completed Application Form
• Research Proposal: Five pages maximum including figures (single spaced, Arial 11 font)

-   Aims
-   Background
-   Preliminary Data
-   Approach

• References
• Proposed budget and justification, including to show how funds (up to $100,000 total) will be allocated across each participating laboratory (two-year budget period starting on November 1)
• NIH Biosketch and Other Support forms for PI, co-investigator(s) and any key personnel
• One reprint or preprint, if desired.

The Letter of Intent and application (pdf) should be forwarded to Anneliese Schaefer, amschaefer@wustl.edu.

Note, if the project is approved for funding, the following materials will be required:

• Animal and/or IRB approvals, if applicable (note that the Hope Center cannot release funds until appropriate approvals are in-place).
• A one-paragraph description of the project and its importance, in language appropriate for the lay public.
• Progress reports at 12 and 24 months, including scientific findings, publications, funding, and intellectual property arising from the project.


Pilot Project Awards

Click below to learn details and progress of active and previous pilot awards.

Active pilot projects

Previous pilot awards

Just-in-Time Funding

In addition to pilot projects, the Hope Center has initiated a funding mechanism to support pressing needs for funds to generate pilot data.

JIT Funding